ID A0A077EEF2_9FLAO Unreviewed; 475 AA.
AC A0A077EEF2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Anthranilate synthase component 1 {ECO:0000256|ARBA:ARBA00020653};
GN ORFNames=BD94_2122 {ECO:0000313|EMBL:AIL45897.1};
OS Elizabethkingia anophelis NUHP1.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Elizabethkingia.
OX NCBI_TaxID=1338011 {ECO:0000313|EMBL:AIL45897.1, ECO:0000313|Proteomes:UP000028933};
RN [1] {ECO:0000313|EMBL:AIL45897.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NUHP1 {ECO:0000313|EMBL:AIL45897.1};
RX PubMed=24012265; DOI=10.1016/S0140-6736(13)61858-9;
RA Teo J., Tan S.Y., Tay M., Ding Y., Kjelleberg S., Givskov M., Lin R.T.,
RA Yang L.;
RT "First case of E anophelis outbreak in an intensive-care unit.";
RL Lancet 382:855-856(2013).
RN [2] {ECO:0000313|EMBL:AIL45897.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NUHP1 {ECO:0000313|EMBL:AIL45897.1};
RX PubMed=26019164; DOI=10.1093/gbe/evv101;
RA Li Y., Liu Y., Chew S.C., Tay M., Salido M.M., Teo J., Lauro F.M.,
RA Givskov M., Yang L.;
RT "Complete Genome Sequence and Transcriptomic Analysis of the Novel Pathogen
RT Elizabethkingia anophelis in Response to Oxidative Stress.";
RL Genome Biol. Evol. 7:1676-1685(2015).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBUNIT: Heterotetramer consisting of two non-identical subunits: a
CC beta subunit (TrpG) and a large alpha subunit (TrpE).
CC {ECO:0000256|ARBA:ARBA00011575}.
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DR EMBL; CP007547; AIL45897.1; -; Genomic_DNA.
DR RefSeq; WP_024564292.1; NZ_CP007547.1.
DR AlphaFoldDB; A0A077EEF2; -.
DR STRING; 1338011.BD94_2122; -.
DR KEGG; eao:BD94_2122; -.
DR eggNOG; COG0147; Bacteria.
DR HOGENOM; CLU_006493_9_4_10; -.
DR Proteomes; UP000028933; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR006805; Anth_synth_I_N.
DR InterPro; IPR015890; Chorismate_C.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF48; ISOCHORISMATE SYNTHASE MENF; 1.
DR Pfam; PF04715; Anth_synt_I_N; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR PRINTS; PR00095; ANTSNTHASEI.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 19..166
FT /note="Anthranilate synthase component I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04715"
FT DOMAIN 208..458
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
FT COILED 445..472
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 475 AA; 54018 MW; 5E93734D8811A35E CRC64;
MNFNQNINIT TKHKNYLSDL YTPIGIYLRL RDRYRDTILL ESAGNQNTDN NYSFICVNAI
SGIEIKSLTE IEVKFPNQAP EKHQLGSEKL TQVLQEFSNC FVPEKSEHPL ANLAQGLYGY
TSYDAVQFFD TVKFKQASPE TDIPLMRYRL YQYVIAINHF NDEMTIFENK IKGLESDFST
LETFINQKNA PVFPFETKDE EKSNLTDEEM AELVEMAKKH AMRGDTFQMV LSRRFEQQFS
GDEFNVYRAL RNINPSPYLF YFDYGSYKIF GSSPESQLII KDQKAIIHPI AGTFKRTGNV
ETDLASAEAL RKDPKENAEH TMLVDLARND LSIMGKNTTV SKLKEIHFFS HVIHMVSEVT
ADVAKGTNPF EMIATTFPQG TLSGAPKYMA MELIDKYEKT SRGYYGGCIG YVGFDGSCNQ
AIMIRTFLSK NNTLYYQAGA GVVAKSDTQS EVQEVKNKLN ALKSALKKAN KMVNY
//
