ID A0A077LY27_9MICO Unreviewed; 332 AA.
AC A0A077LY27;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=alcohol dehydrogenase {ECO:0000256|ARBA:ARBA00013190};
DE EC=1.1.1.1 {ECO:0000256|ARBA:ARBA00013190};
GN ORFNames=BN12_300019 {ECO:0000313|EMBL:CCH78571.1}, BN12_4190010
GN {ECO:0000313|EMBL:CCH79370.1};
OS Tetrasphaera japonica T1-X7.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Tetrasphaera.
OX NCBI_TaxID=1194083 {ECO:0000313|EMBL:CCH78571.1, ECO:0000313|Proteomes:UP000035721};
RN [1] {ECO:0000313|EMBL:CCH78571.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=T1-X7 {ECO:0000313|EMBL:CCH78571.1};
RA McIlroy S.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCH78571.1, ECO:0000313|Proteomes:UP000035721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T1-X7 {ECO:0000313|EMBL:CCH78571.1,
RC ECO:0000313|Proteomes:UP000035721};
RX PubMed=23178666; DOI=10.1038/ismej.2012.136;
RA Kristiansen R., Nguyen H.T.T., Saunders A.M., Nielsen J.L., Wimmer R.,
RA Le V.Q., McIlroy S.J., Petrovski S., Seviour R.J., Calteau A.,
RA Nielsen K.L., Nielsen P.H.;
RT "A metabolic model for members of the genus Tetrasphaera involved in
RT enhanced biological phosphorus removal.";
RL ISME J. 7:543-554(2013).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH78571.1}.
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DR EMBL; CAJB01000224; CCH78571.1; -; Genomic_DNA.
DR EMBL; CAJB01000356; CCH79370.1; -; Genomic_DNA.
DR RefSeq; WP_048550806.1; NZ_HF570958.1.
DR AlphaFoldDB; A0A077LY27; -.
DR STRING; 1194083.BN12_300019; -.
DR OrthoDB; 3567264at2; -.
DR Proteomes; UP000035721; Unassembled WGS sequence.
DR GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08298; CAD2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR014187; ADH_Zn_typ-2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR NCBIfam; TIGR02822; adh_fam_2; 1.
DR PANTHER; PTHR42940; ALCOHOL DEHYDROGENASE 1-RELATED; 1.
DR PANTHER; PTHR42940:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11; 1.
DR Pfam; PF08240; ADH_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CCH78571.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000035721}.
FT DOMAIN 15..330
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 332 AA; 35033 MW; AEAE3F7EE40022CC CRC64;
MRAWHVTTPA PVERGPVALT DRPIPDPAPG ELLVQVLACG VCRTDLHVTE GDLPVHRPGV
VPGHEVVGRV VAVGATAEGY TVGDRVGIAW LRHTDGACRW CRRGAENLCP ASRYTGWDAD
GGYAEYTTVP ADFAYAVPDG IDDVAAAPLL CAGIIGYRAL ARASVPEGGV LGLYGFGGSA
HLTAQLAVAQ GARVHVMTRG EQARELARSL GAASVQDFDD PPPEPLDSAI TFAPVGTAVP
MIMRALGRGG VLAVAGIHLS DIPALRYEEE LFYEKQLRSV TSNTREDGRA FLQLAVRHGI
RATTHTYPLD GALEALRDLK AGRFDGAAVL VP
//
