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Database: UniProt
Entry: A0A077RD29_ECHMU
LinkDB: A0A077RD29_ECHMU
Original site: A0A077RD29_ECHMU 
ID   A0A077RD29_ECHMU        Unreviewed;       448 AA.
AC   A0A077RD29;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   10-MAY-2017, entry version 13.
DE   SubName: Full=Nicastrin {ECO:0000313|EMBL:CDI97624.1};
GN   ORFNames=EmuJ_000141400 {ECO:0000313|EMBL:CDI97624.1};
OS   Echinococcus multilocularis (Fox tapeworm).
OC   Eukaryota; Metazoa; Platyhelminthes; Cestoda; Eucestoda;
OC   Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6211 {ECO:0000313|EMBL:CDI97624.1, ECO:0000313|Proteomes:UP000017246};
RN   [1] {ECO:0000313|EMBL:CDI97624.1, ECO:0000313|Proteomes:UP000017246}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Java {ECO:0000313|Proteomes:UP000017246};
RX   PubMed=23485966; DOI=10.1038/nature12031;
RA   Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A.,
RA   Sanchez-Flores A., Brooks K.L., Tracey A., Bobes R.J., Fragoso G.,
RA   Sciutto E., Aslett M., Beasley H., Bennett H.M., Cai J., Camicia F.,
RA   Clark R., Cucher M., De Silva N., Day T.A., Deplazes P., Estrada K.,
RA   Fernandez C., Holland P.W., Hou J., Hu S., Huckvale T., Hung S.S.,
RA   Kamenetzky L., Keane J.A., Kiss F., Koziol U., Lambert O., Liu K.,
RA   Luo X., Luo Y., Macchiaroli N., Nichol S., Paps J., Parkinson J.,
RA   Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M., Salinas G.,
RA   Wasmuth J.D., Zamanian M., Zheng Y., Taenia solium Genome Consortium,
RA   Cai X., Olson P.D., Laclette J.P., Brehm K., Berriman M.;
RT   "The genomes of four tapeworm species reveal adaptations to
RT   parasitism.";
RL   Nature 496:57-63(2013).
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DR   EMBL; LN902844; CDI97624.1; -; Genomic_DNA.
DR   GeneDB; EmuJ_000141400.1:pep; -.
DR   Proteomes; UP000017246; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016485; P:protein processing; IEA:InterPro.
DR   InterPro; IPR008710; Nicastrin.
DR   PANTHER; PTHR21092; PTHR21092; 1.
DR   Pfam; PF05450; Nicastrin; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000017246};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017246};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     40     59       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    409    432       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   448 AA;  49478 MW;  0ED0F2031AAF5102 CRC64;
     MLRARNLTAT NSSSTKPDPT ILVVSRVDAL SMFDRRATSA LAVLPAVSVM VSAAVHLLNQ
     LDVRAGRMRK NLLFLLLDNE ALSFMGSQRF LFDLTHGRVA QASGLPLNVD SVESVIELAG
     IGLPREDDRK LPIYYLLCDP GIAQQTENIT SSIWRALNAS ADDQGSTVRF LNGSLVPPAL
     LPPSLSTQAL LRYFVRKGRP LSHIVISDRP ATPPFADTFI DSFLDTRWPP SPTANSYLLR
     LANLLADALH REITEDSSPI PEPISGVKPA ELMDCFLKDP GCNLLRMHLE PEVVNFLLSL
     KGPIPMQTYE PVDGHSWRVS HVVSHLLMGL TGHRLKECPP STDYGAFTYM YGYYNGSTWC
     YQSLVETATS FFFLEDGAVA APGWVRSVPF ENQRFVRLFR SAPPSNDKLA LALGIILTAI
     TGLIALLVRA FADRLFVRTY DSHLPQSR
//
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