ID A0A077RQS0_WHEAT Unreviewed; 666 AA.
AC A0A077RQS0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Bicarbonate transporter-like transmembrane domain-containing protein {ECO:0000259|Pfam:PF00955};
GN ORFNames=CFC21_040395 {ECO:0000313|EMBL:KAF7028474.1},
GN TRAES_3BF021800230CFD_c1 {ECO:0000313|EMBL:CDM81925.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EMBL:CDM81925.1};
RN [1] {ECO:0000313|EMBL:CDM81925.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25035497; DOI=10.1126/science.1249721;
RA Choulet F., Alberti A., Theil S., Glover N., Barbe V., Daron J.,
RA Pingault L., Sourdille P., Couloux A., Paux E., Leroy P., Mangenot S.,
RA Guilhot N., Le Gouis J., Balfourier F., Alaux M., Jamilloux V., Poulain J.,
RA Durand C., Bellec A., Gaspin C., Safar J., Dolezel J., Rogers J.,
RA Vandepoele K., Aury J.M., Mayer K., Berges H., Quesneville H., Wincker P.,
RA Feuillet C.;
RT "Structural and functional partitioning of bread wheat chromosome 3B.";
RL Science 345:1249721-1249721(2014).
RN [2] {ECO:0000313|EMBL:KAF7028474.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7028474.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3B02G145500.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3B02G145500.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [4] {ECO:0000313|EnsemblPlants:TraesCS3B02G145500.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [5] {ECO:0000313|EMBL:KAF7028474.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7028474.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31.3) family.
CC {ECO:0000256|ARBA:ARBA00006262}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HG670306; CDM81925.1; -; Genomic_DNA.
DR EMBL; CM022218; KAF7028474.1; -; Genomic_DNA.
DR EnsemblPlants; TraesCS3B02G145500.1; TraesCS3B02G145500.1; TraesCS3B02G145500.
DR Gramene; TraesCS3B02G145500.1; TraesCS3B02G145500.1; TraesCS3B02G145500.
DR Gramene; TraesCS3B03G0346600.1; TraesCS3B03G0346600.1.CDS; TraesCS3B03G0346600.
DR Gramene; TraesWEE_scaffold_047080_01G000300.1; TraesWEE_scaffold_047080_01G000300.1; TraesWEE_scaffold_047080_01G000300.
DR eggNOG; KOG1172; Eukaryota.
DR HOGENOM; CLU_002289_3_2_1; -.
DR OrthoDB; 34804at2759; -.
DR Proteomes; UP000019116; Chromosome 3B.
DR Proteomes; UP000815260; Chromosome 3B.
DR ExpressionAtlas; A0A077RQS0; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR GO; GO:0006820; P:monoatomic anion transport; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF40; BORON TRANSPORTER 4-RELATED; 1.
DR Pfam; PF00955; HCO3_cotransp; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 550..579
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..180
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT DOMAIN 205..375
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT DOMAIN 457..547
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 610..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..656
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 74494 MW; F7C14981757940D4 CRC64;
MDLLGNPFKG VVADVQGRAS WYKDDWVAGL RTGFRILAPT MYIFFASALP VISFGEQLSN
ETDGILSTVE TLASTAICGI IHSILGGQPL LIVGVAEPTI IMYTYLYKFA RKQPDLGEQL
YLAWAGWVCI WTSIMLFLLA MFNASNVISR FTRVAGELFG MLITVLFLQQ AIKGIVSEFS
MPKDDEISDP SSPIYQFQWI YVNGLLGVIF SIGLLYTALK TRRARSWLYG IGWLRSFIAD
YGVPLMVIVW TAFSFALPSK VPSGVPRRLF SPLPWESISL RHWTVAKDLF SVPPTYIFAA
IVPALMVAGL YFFDHSVASQ LAQQKEFNLK KPSAYHYDIL VLGFMVLLCG LLGIPPSNGV
LPQSPMHTRS LAVLKGQLLR KKMLQTAKEG MSNRASSLEI YGKMQEVFIQ MDSNMNANSV
DKDLKSLKDA VLREGDEEGK LAGEFDPSKY IEAHLPVRVN EQRLSNLLQS LLVGGCVGAM
PVLKMIPTSV LWGYFAYMAI DSLPGNQFWE RLQLLCIGAS RRYKVLEGPH ASFVESVPSR
TISAFTVFQF VYLLICFGIT WIPVAGILFP LPFFIMILIR QHLLPKFFEP NDLRELDAAE
YEELEGVPHE QILEEDGSDS GSCDSRDDSE ILDELTTNRG ELKHRTVNHP EERHLQVHSN
AVQPSV
//
