ID A0A077YY47_TRITR Unreviewed; 501 AA.
AC A0A077YY47;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Alpha (1,6) fucosyltransferase {ECO:0000313|EMBL:CDW52701.1};
GN ORFNames=TTRE_0000096301 {ECO:0000313|EMBL:CDW52701.1};
OS Trichuris trichiura (Whipworm) (Trichocephalus trichiurus).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=36087 {ECO:0000313|EMBL:CDW52701.1};
RN [1] {ECO:0000313|EMBL:CDW52701.1}
RP NUCLEOTIDE SEQUENCE.
RA Aslett M.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDW52701.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Foth B.J., Tsai I.J., Reid A.J., Bancroft A.J., Nichol S., Tracey A.,
RA Holroyd N., Cotton J.A., Stanley E.J., Zarowiecki M., Liu J.Z.,
RA Huckvale T., Cooper P.J., Grencis R.K., Berriman M.;
RT "The whipworm genome and dual-species transcriptomics of an intimate host-
RT pathogen interaction.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 23 family.
CC {ECO:0000256|PROSITE-ProRule:PRU00992}.
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DR EMBL; HG805829; CDW52701.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A077YY47; -.
DR STRING; 36087.A0A077YY47; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR CDD; cd11300; Fut8_like; 1.
DR CDD; cd11792; SH3_Fut8; 1.
DR Gene3D; 3.40.50.11350; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR045573; Fut8_N_cat.
DR InterPro; IPR035653; Fut8_SH3.
DR InterPro; IPR027350; GT23_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR13132; ALPHA- 1,6 -FUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR13132:SF29; ALPHA-(1,6)-FUCOSYLTRANSFERASE; 1.
DR Pfam; PF19745; FUT8_N_cat; 2.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51659; GT23; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676, ECO:0000256|PROSITE-
KW ProRule:PRU00992}; Membrane {ECO:0000256|ARBA:ARBA00023136};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00992}; Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 148..416
FT /note="GT23"
FT /evidence="ECO:0000259|PROSITE:PS51659"
FT DOMAIN 425..486
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 296..297
FT /note="Important for donor substrate binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00992"
SQ SEQUENCE 501 AA; 58221 MW; 86BF8CA1132E0606 CRC64;
MLRLTKLTIF VVSLCVLCFF VAVVLVSKLS FPADPARLRE RNNSWMILAR LLETQKQLEY
FSQKTHQLQD QVKQIEIRIY GKWCVWKTFL GSINGYLGIS VTLYSKLFDS QVCYLRSLVA
LSLRKLHQLS KVVQNQLYDL QHPLSCEKAR RLICSLDKPC GFACQVHHVT YCLQVAYYTN
RTMVLNDNSW SYSSHGWTSV FQPVSNSCRY NYDEETPRVG KCNCRILTLR GKLVCFSLLL
SSKRFRLLRL HSYPPAWWTG ELVSYLMRYN SEMSDKLEQM ATLYNFSYPI VGIHVRRTDK
VGTEARFHGL EEYMVEVEKC PGQKRKVYIA TDDPSVFSEA RRTYPNYTFI GSSDVARTAD
LKWRYSDTSL QGIVTDIHFL SLSNFLVCTF SSQVCRLAYE KMQHLYGDAG YNFRSLDDIY
YYGGQREHTW LAVMDHVPRK SDEIELRRGD RIAVAGNHWD GYSKGTNMRT SVSGLFPTYK
TVETWRFAKT PFSWLNATTL I
//
