ID   A0A077Z141_TRITR        Unreviewed;       298 AA.
AC   A0A077Z141;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Resistance to inhibitors of {ECO:0000313|EMBL:CDW53438.1};
GN   ORFNames=TTRE_0000170301 {ECO:0000313|EMBL:CDW53438.1};
OS   Trichuris trichiura (Whipworm) (Trichocephalus trichiurus).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichuridae; Trichuris.
OX   NCBI_TaxID=36087 {ECO:0000313|EMBL:CDW53438.1};
RN   [1] {ECO:0000313|EMBL:CDW53438.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Aslett M.;
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDW53438.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Foth B.J., Tsai I.J., Reid A.J., Bancroft A.J., Nichol S., Tracey A.,
RA   Holroyd N., Cotton J.A., Stanley E.J., Zarowiecki M., Liu J.Z.,
RA   Huckvale T., Cooper P.J., Grencis R.K., Berriman M.;
RT   "The whipworm genome and dual-species transcriptomics of an intimate host-
RT   pathogen interaction.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ric-3 family.
CC       {ECO:0000256|ARBA:ARBA00008538}.
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DR   EMBL; HG805853; CDW53438.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A077Z141; -.
DR   STRING; 36087.A0A077Z141; -.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR026160; Ric3.
DR   InterPro; IPR032763; RIC3_N.
DR   PANTHER; PTHR21723; RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3; 1.
DR   PANTHER; PTHR21723:SF3; RIC3 ACETYLCHOLINE RECEPTOR CHAPERONE, ISOFORM C; 1.
DR   Pfam; PF15361; RIC3; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          24..179
FT                   /note="Resistance to inhibitors of cholinesterase protein 3
FT                   N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15361"
FT   COILED          160..208
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   298 AA;  34073 MW;  DAE80B0777964424 CRC64;
     MAEEAAQITR RKTLAVFLVV TVSAVVVYPK FIHPKLFSAL GLFRQKPETE FDDVRNGRQQ
     PRLQQVHRPY DETGRKAYDH LPLNYGAHLA GPRREKGFWS SLLPFYSIGV IAFLAYTLSK
     MWLKTDTNGV RDEHALWLTS LFRNGRESGS YFGSLNDNQL KRLREQLLET EEAMQKILEG
     LESDNVSNNT ARNEFQEALA SLKRLTDLTA GKLLCHFEES RPQPSLEPNI EDLLHDLENV
     LDRFGLSKEA SRQAPEKANF DSRCDKITED APLTRLQRLQ SDLSVSERPT ELNSKKIV
//