ID A0A077Z450_TRITR Unreviewed; 702 AA.
AC A0A077Z450;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=LRR 8 and LRRNT and I-set and fn3 domain containi ng protein {ECO:0000313|EMBL:CDW54831.1};
GN ORFNames=TTRE_0000310101 {ECO:0000313|EMBL:CDW54831.1};
OS Trichuris trichiura (Whipworm) (Trichocephalus trichiurus).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=36087 {ECO:0000313|EMBL:CDW54831.1};
RN [1] {ECO:0000313|EMBL:CDW54831.1}
RP NUCLEOTIDE SEQUENCE.
RA Aslett M.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDW54831.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Foth B.J., Tsai I.J., Reid A.J., Bancroft A.J., Nichol S., Tracey A.,
RA Holroyd N., Cotton J.A., Stanley E.J., Zarowiecki M., Liu J.Z.,
RA Huckvale T., Cooper P.J., Grencis R.K., Berriman M.;
RT "The whipworm genome and dual-species transcriptomics of an intimate host-
RT pathogen interaction.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG805917; CDW54831.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A077Z450; -.
DR STRING; 36087.A0A077Z450; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45842:SF12; KEKKON 5, ISOFORM A; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF00560; LRR_1; 2.
DR Pfam; PF13855; LRR_8; 3.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00369; LRR_TYP; 9.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..702
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001728386"
FT TRANSMEM 634..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 425..517
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 517..613
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 702 AA; 79259 MW; BB1DE7CBB157EF6A CRC64;
MRLASKFALS LLCIFYANVE ALWPADDCPT PCRCELRHSE RFQELLKTVD CFDSELTAFP
ENLPTETQVL ILRQNHIRLL PSQELWLPDL VHLDLSHNRI SSLTSEDFRE YVFDGVYNLR
VLDLSFNHLR RLRSNDFRGL FNLEELSLAD NRIGSIADNA FHGLLKLEAL RLTGNRLAFI
QSGWFSGLKT LTTLLLNRNQ LTILTSDNFR SLSELLTLDL SRNKIFHVHE NAFAGIGKLD
SLRLSSNVLT IVPHQALRRL GSLRSVNLSQ NPIYKVRTDD FANLPRLRDV NLSTMQRLRL
IERGAFKNLP ELLVVELHDN PYLGYVDRLS FVNTPSVSHL FLHNNNLTTV EEEVIDRLDN
LQEVSLYGNP LRCDCNIRWM SLSISARSRI TYHEAERMLC DSPPEHKYKL FVSLNVSSIA
TTCPPRILYT FAPTENRKPG DTQAYDCRAV GIPQPEIRWT TADGQTIDPT VYHPRRSVIN
GQTLVLNHLT KEDQGTYICR AENTEGRSER ATTLNVTEMQ VHLFPVQVSA TSVTVTWNGT
DAQNGGGTVF QIFYRPSELS GRHQYAGTVT PIMRTYTIQN LQPNSAYDIC IAMEDGDDVV
VHLSCKRLKT LNLDPTSAQQ RQQLLRSRAS GTTVGAILGI VACVLIVLCL IVVALLRARI
AQRRTGGKFS RLSDFVAQLE SGVVVASLDQ LAELKARGYS IV
//
