ID A0A077Z6X3_TRITR Unreviewed; 809 AA.
AC A0A077Z6X3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Phospholipase A 2 activating protein {ECO:0000313|EMBL:CDW56172.1};
GN ORFNames=TTRE_0000444701 {ECO:0000313|EMBL:CDW56172.1};
OS Trichuris trichiura (Whipworm) (Trichocephalus trichiurus).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=36087 {ECO:0000313|EMBL:CDW56172.1};
RN [1] {ECO:0000313|EMBL:CDW56172.1}
RP NUCLEOTIDE SEQUENCE.
RA Aslett M.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDW56172.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Foth B.J., Tsai I.J., Reid A.J., Bancroft A.J., Nichol S., Tracey A.,
RA Holroyd N., Cotton J.A., Stanley E.J., Zarowiecki M., Liu J.Z.,
RA Huckvale T., Cooper P.J., Grencis R.K., Berriman M.;
RT "The whipworm genome and dual-species transcriptomics of an intimate host-
RT pathogen interaction.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the WD repeat PLAP family.
CC {ECO:0000256|ARBA:ARBA00008495}.
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DR EMBL; HG806015; CDW56172.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A077Z6X3; -.
DR STRING; 36087.A0A077Z6X3; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0043170; P:macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.10.20.870; PFU (PLAA family ubiquitin binding), C-terminal domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015155; PFU.
DR InterPro; IPR038122; PFU_sf.
DR InterPro; IPR013535; PUL_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19849; PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR19849:SF0; PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; 1.
DR Pfam; PF09070; PFU; 1.
DR Pfam; PF08324; PUL; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51394; PFU; 1.
DR PROSITE; PS51396; PUL; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 8..42
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 105..136
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 188..228
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 229..270
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 372..470
FT /note="PFU"
FT /evidence="ECO:0000259|PROSITE:PS51394"
FT DOMAIN 530..804
FT /note="PUL"
FT /evidence="ECO:0000259|PROSITE:PS51396"
SQ SEQUENCE 809 AA; 90744 MW; 12DB4DCF028DEAE3 CRC64;
MFEIRQHLVG HESDVRCIAQ FTSKDSLCLV SGSQDGTVCV WKEQPVSGTM AFAEHYRIKS
GSETVAAICE MPSCDQYPNG AIVAACADRK IRLYDGETFQ LLKMLQGHDN RVCCLAVSEE
TGELASGSWD CTARVWRPND EWAEYIGHSG TVWAVAFLKF EGKLRLLSAS ADKLIFLWGD
DCCPLRSYHG HTDCVRGLYV TSSQQFYSCS NDGTIRMWQA DYASSLRTYT GHEHFIFSIS
SRETLPYFAS GSEDHTVRVW EKETNKCLQT FRLPCQTVWG VVIMSNGDIA CACSDATIRI
FSSCDERKAI PEKISAYEQV LAAFELSMQA NDRTGNSTYS DLPTVDILNR PGSRDGQTML
LRDSRRRLQA FSWSSEERRW NCVGPAIEKS IALKKTEKTV YEGKEYDCVF EIDVADDQPH
LKLPYNFGDD PWTCAQQFIT KHKLPPTYLE KVADFVVESS ARVANQNSFA TTSIDPFVGS
SRQIAAGTCD DSNKSKSDVS DPFTGSARYI PSYSSDFKVP MFDPFKPRGC GMPTREYYTF
NSVNAEGLTA KLKVFNVAVD SKLAIEPAHL VILENFARNT DDVITDEALD SLRRCLCWPE
EFLLPVVDCL RLVLLTEKGN DYFFYNHPGM EFLNQLCSFM QTNGKRQGHS DMLLVVVLRA
LSNSFVHQSG RDVMYLCDEK FWANVCEALK ATKTSAQVAA SSAIANVTYL YASQVNHLEA
TDRKVRLLGV LVEKLTGIFE AGDVNFDAAI LLRISQALIT LMWGDYDVVK YAKTMNLEYV
LSKLKDASSN EFDKKDLIGK METMLKAVD
//
