ID A0A077Z9H6_TRITR Unreviewed; 593 AA.
AC A0A077Z9H6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Transient-receptor-potential-like protein {ECO:0000313|EMBL:CDW56434.1};
GN ORFNames=TTRE_0000471401 {ECO:0000313|EMBL:CDW56434.1};
OS Trichuris trichiura (Whipworm) (Trichocephalus trichiurus).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=36087 {ECO:0000313|EMBL:CDW56434.1};
RN [1] {ECO:0000313|EMBL:CDW56434.1}
RP NUCLEOTIDE SEQUENCE.
RA Aslett M.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDW56434.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Foth B.J., Tsai I.J., Reid A.J., Bancroft A.J., Nichol S., Tracey A.,
RA Holroyd N., Cotton J.A., Stanley E.J., Zarowiecki M., Liu J.Z.,
RA Huckvale T., Cooper P.J., Grencis R.K., Berriman M.;
RT "The whipworm genome and dual-species transcriptomics of an intimate host-
RT pathogen interaction.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HG806039; CDW56434.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A077Z9H6; -.
DR STRING; 36087.A0A077Z9H6; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR013555; TRP_dom.
DR InterPro; IPR002153; TRPC_channel.
DR PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR PANTHER; PTHR10117:SF47; TRANSIENT-RECEPTOR-POTENTIAL-LIKE PROTEIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF08344; TRP_2; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM01420; TRP_2; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:CDW56434.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 306..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 554..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 119..148
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 151..214
FT /note="Transient receptor ion channel"
FT /evidence="ECO:0000259|SMART:SM01420"
SQ SEQUENCE 593 AA; 69130 MW; 9B0FB99DBE7938DF CRC64;
MVNQKPLVEE FKPPPDLTEI DPFLLMDEGR IDELLEMLTK EPYRIEAESH YYVTPIMHAL
VTRKVDVFNW LIGKSVYRFR DAVLTAVLIG DTFNVELLLK IRAFDDDDEP PKSFPVCMTP
LMLAAHCDNY EMIKLLLKLG HKLDLPHRPD CKCKACRTEN DEHVVAVNRR RLYSYRAISS
HAYLLQDCIQ DPVIDCFLIA RDLEKCQQHD EAYAEKYGEM AKHVKEVPLA FLNSCCNESE
ATLMLSQLEG SRLSDVTALP RVSVAMDTRQ KEFITSRHCM EILKKQWMGG WNDWDRASWI
TKQFRLLSHT IFYPLTCMLY LLTNGKAAKS YNYPVARKHF SRVFVSRFPT ICYRYDFLQL
ITYLLAFHSF LVSAIVVHNH GEPYLHRMHW DPLHPTLLFE VLFTIAAVLS SWRLFYFLQI
IRRFGPLVIS IGKCVKDILL FWVIFVVVLG SFAVGLNYLI EHYKYNIVVR DGKTIEQQFY
MTRQVDMLNK TQTIRYYYCF DNLFIQSAMR YLYWAWYGYL DPERLEVIVG NSCPESLETK
HVIIQNAAEF LSAVYYMILV ISLLNLMISL MATTAGTVLV SSRFPTPARG QLI
//
