ID A0A077ZB40_TRITR Unreviewed; 501 AA.
AC A0A077ZB40;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 22-FEB-2023, entry version 29.
DE SubName: Full=Suppressor of hairless protein {ECO:0000313|EMBL:CDW55870.1};
GN ORFNames=TTRE_0000414401 {ECO:0000313|EMBL:CDW55870.1};
OS Trichuris trichiura (Whipworm) (Trichocephalus trichiurus).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=36087 {ECO:0000313|EMBL:CDW55870.1};
RN [1] {ECO:0000313|EMBL:CDW55870.1}
RP NUCLEOTIDE SEQUENCE.
RA Aslett M.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDW55870.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Foth B.J., Tsai I.J., Reid A.J., Bancroft A.J., Nichol S., Tracey A.,
RA Holroyd N., Cotton J.A., Stanley E.J., Zarowiecki M., Liu J.Z.,
RA Huckvale T., Cooper P.J., Grencis R.K., Berriman M.;
RT "The whipworm genome and dual-species transcriptomics of an intimate host-
RT pathogen interaction.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the Su(H) family.
CC {ECO:0000256|ARBA:ARBA00009704}.
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DR EMBL; HG805988; CDW55870.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A077ZB40; -.
DR STRING; 36087.A0A077ZB40; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.1450; LAG1, DNA binding domain; 1.
DR InterPro; IPR015350; Beta-trefoil_DNA-bd_dom.
DR InterPro; IPR036358; BTD_sf.
DR InterPro; IPR040159; CLS_fam.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR015351; RBP-J/Cbf11/Cbf12_DNA-bd.
DR InterPro; IPR037095; RBP-J/Cbf11_DNA-bd_sf.
DR InterPro; IPR038007; RBP-Jkappa_IPT.
DR PANTHER; PTHR10665; RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS; 1.
DR PANTHER; PTHR10665:SF0; SUPPRESSOR OF HAIRLESS PROTEIN; 1.
DR Pfam; PF09270; BTD; 1.
DR Pfam; PF09271; LAG1-DNAbind; 1.
DR Pfam; PF20144; TIG_SUH; 1.
DR SMART; SM01268; BTD; 1.
DR SMART; SM01267; LAG1_DNAbind; 1.
DR SUPFAM; SSF110217; DNA-binding protein LAG-1 (CSL); 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 69..207
FT /note="RBP-J/Cbf11/Cbf12 DNA binding"
FT /evidence="ECO:0000259|SMART:SM01267"
FT DOMAIN 211..359
FT /note="Beta-trefoil DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01268"
SQ SEQUENCE 501 AA; 56786 MW; 773DCAD778F560BA CRC64;
MCALRMFVGW SRRRKRWFPC VSAVGHVPVS VRNIPHQPSY NCFLFVRPSV VKLTRESMQR
YLNGGLGCVI TIFHAKVAQK SYGSEKRFFC PPPSVYLSGE GWKHKQQQVT SMCQSQEVDK
SSHTSELVVT IGIGNMEQED QVLEFPSGKN FCSAKNLFIS DSDKRKYFEL LVNLTYTCGY
DVGLFSSQRI KVISKPSKKK QSMKNTDCKY LCIASGTKVA LFNRLRSQTV STRYLHVRGG
CFYASSTQWG AFAIHLLEDD ATEAEEFSVR DGFIHYGSTV KLVDSVSGIA LPRLVIRRIE
KQMALLDSEE PVSQLHKCAF YMKDTNCMYL CLSQDRIIQY QAQPSRESNK HIITDSAAWT
IISTEKAEYR FYEAMGPASA PVTPVPIVRS LHFNGGGDSA YVELCGSNFM PGLKVWFGDV
EANTVFRGEQ MLYCSVPPIS RFRPEWLSSD DNHSVPISLV RFDGVIYYTG MRFTYTPEKP
LISTVRRDSA FPRRQSLESC Q
//
