ID   A0A077ZS96_STYLE        Unreviewed;       623 AA.
AC   A0A077ZS96;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   28-JUN-2023, entry version 17.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   Name=Contig14575.g15527 {ECO:0000313|EMBL:CDW72768.1};
GN   ORFNames=STYLEM_1732 {ECO:0000313|EMBL:CDW72768.1};
OS   Stylonychia lemnae (Ciliate).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Stylonychia.
OX   NCBI_TaxID=5949 {ECO:0000313|EMBL:CDW72768.1, ECO:0000313|Proteomes:UP000039865};
RN   [1] {ECO:0000313|EMBL:CDW72768.1, ECO:0000313|Proteomes:UP000039865}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=130c {ECO:0000313|EMBL:CDW72768.1,
RC   ECO:0000313|Proteomes:UP000039865};
RA   Swart Estienne;
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CCKQ01001653; CDW72768.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A077ZS96; -.
DR   EnsemblProtists; CDW72768; CDW72768; STYLEM_1732.
DR   InParanoid; A0A077ZS96; -.
DR   OrthoDB; 5626938at2759; -.
DR   Proteomes; UP000039865; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000039865};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        453..475
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        487..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        510..528
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        601..622
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          59..245
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   623 AA;  71385 MW;  E6172D6D3A108464 CRC64;
     MMIFYIIASL YNFITSNYDI SGQITYSIIS DKMAVSDIQI KVNNSIWDSY QVDIYNKSAV
     FLCVDRSGSM GTLLGQQKRI DVVKDQILSF AKTFFTKDLT KNVTLYVTFY DDEVDTQGFT
     DYQSLQAYMN DKSTPGGDTG FYLALQDVLS KVKENNLQNI HVYLLSDGQD SYPDDTQKVM
     KSLHTYLTQN SIHSRFSAIG IAQPDTQTMS EIINLGTISG DYVYVDESKS SDTQIQQINQ
     FYDLINTYVF NQPKGITLTI LDETIFLKLF KDGATQTHQV FLLTGHIFNL QDIKTYLGKL
     KGILEDKSYH YSNISLVKKN IGYDDNKDLL VIYNSVVQLN FDLTRQIVKA DIDDIQAQIN
     GNLKDSLKQD IKKDYQYIDS QLKNMEIVIN NNQDKNLNVK ERGSVEQYRN FVLKRFEDRQ
     LEVFDASSPD EKDDLDDGTG DSDTKTDTKA MRVVIGIKHI FEVIITITIF LFYAIRCKCS
     FIKFRICCIY VFVAYIVLLV QDFILMAPPI WIFIYHVALL MIIFVVSLRK KDPSQEGNDR
     TDSLQRVSLN PNNYVQINEQ NEEVEVREDD QANAAANKKP GVVFSKTYRE EFLKSSSLTK
     IAFMAFLFME LTLSICIIAL ALQ
//