ID A0A077ZUG0_STYLE Unreviewed; 525 AA.
AC A0A077ZUG0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Diacylglycerol kinase eta {ECO:0000256|ARBA:ARBA00017201};
DE EC=2.7.1.107 {ECO:0000256|ARBA:ARBA00012133};
GN Name=Contig14684.g15641 {ECO:0000313|EMBL:CDW73512.1};
GN ORFNames=STYLEM_2492 {ECO:0000313|EMBL:CDW73512.1};
OS Stylonychia lemnae (Ciliate).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Stylonychia.
OX NCBI_TaxID=5949 {ECO:0000313|EMBL:CDW73512.1, ECO:0000313|Proteomes:UP000039865};
RN [1] {ECO:0000313|EMBL:CDW73512.1, ECO:0000313|Proteomes:UP000039865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=130c {ECO:0000313|EMBL:CDW73512.1,
RC ECO:0000313|Proteomes:UP000039865};
RA Swart Estienne;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Phosphorylates diacylglycerol (DAG) to generate phosphatidic
CC acid (PA). {ECO:0000256|ARBA:ARBA00002064}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the eukaryotic diacylglycerol kinase family.
CC {ECO:0000256|ARBA:ARBA00009280}.
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DR EMBL; CCKQ01002424; CDW73512.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A077ZUG0; -.
DR EnsemblProtists; CDW73512; CDW73512; STYLEM_2492.
DR InParanoid; A0A077ZUG0; -.
DR OMA; TNINSMM; -.
DR OrthoDB; 4642163at2759; -.
DR Proteomes; UP000039865; Unassembled WGS sequence.
DR GO; GO:0004143; F:ATP-dependent diacylglycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0007205; P:protein kinase C-activating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR037607; DGK.
DR InterPro; IPR000756; Diacylglycerol_kin_accessory.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR11255; DIACYLGLYCEROL KINASE; 1.
DR PANTHER; PTHR11255:SF34; DIACYLGLYCEROL KINASE ETA; 1.
DR Pfam; PF00609; DAGK_acc; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000039865};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 99..248
FT /note="DAGKc"
FT /evidence="ECO:0000259|SMART:SM00046"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 525 AA; 60362 MW; 0354D9AC8E3F1DE7 CRC64;
MEKRSDFEEI KTNPAMGSPI NYDQSDDRSN FNGKSSINMV DEYQGSLNCV DQIFIEEHPT
NASRLKEHSQ FLTETYNQGS SSQSNLTRKT RVEEIKLYQV FLFANPKSGS QQARFFINQQ
MFEHTFELGK GVQAHLLIHN ILDEQAAKSG YAQIASLQRE DDPTVRIIMV TAGGDGSLIG
IVMKAQEDKK NKVDFDKLLC CPLPYGTGND LSRILKWGGS PDSQYYKKLD RLIQEICLNS
EEQQINLWKV VIKYKEKGAT YIVDSKSRKY VQDHDDFKRY MINYFGMGED GRIGVAFEKN
RTKYRCCNNC IYCWAGFKNF LGCCRNQTIA EQIDYMKVLD DDNQESLIDK KEDSLEEEKS
MRSTEGIKLN QGGRVVFSTN QKDKDNFRLE GNPISIISTN INSMMGGRRN VWNESRNHIG
LKNPYQTQKA PKKPLVQFNN QHFDDDVLEF NSFNTILQMV LTGGYRISQD RGPIQFKFKD
LKKDFYAYLN VDGEYYKMRN PDTATVSLAT DCTKSGKLRL LARKV
//
