ID A0A078ATR0_STYLE Unreviewed; 501 AA.
AC A0A078ATR0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Na+-driven multidrug efflux pump {ECO:0000313|EMBL:CDW84612.1};
GN Name=Contig16416.g17480 {ECO:0000313|EMBL:CDW84612.1};
GN ORFNames=STYLEM_13677 {ECO:0000313|EMBL:CDW84612.1};
OS Stylonychia lemnae (Ciliate).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Stylonychia.
OX NCBI_TaxID=5949 {ECO:0000313|EMBL:CDW84612.1, ECO:0000313|Proteomes:UP000039865};
RN [1] {ECO:0000313|EMBL:CDW84612.1, ECO:0000313|Proteomes:UP000039865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=130c {ECO:0000313|EMBL:CDW84612.1,
RC ECO:0000313|Proteomes:UP000039865};
RA Swart Estienne;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CCKQ01012983; CDW84612.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A078ATR0; -.
DR EnsemblProtists; CDW84612; CDW84612; STYLEM_13677.
DR InParanoid; A0A078ATR0; -.
DR OMA; GQWAIGI; -.
DR OrthoDB; 10858at2759; -.
DR Proteomes; UP000039865; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR11206:SF153; ETHIONINE RESISTANCE-CONFERRING PROTEIN 1; 1.
DR PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR Pfam; PF01554; MatE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000039865};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 56..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 55896 MW; 5F36ADBBC0A7EF0D CRC64;
MDDQKTIRKS LKEPLLGENN DQERNQQTSI NPDTKATAQT QKLDQDLTMT SAMKKIFSLA
IYPIIGMVFH PAYHICNSII LGHDEDPRLL ASLGLGGLTI SIFLLSVGIS FCGSLDTLIS
QAFGQKDFRL CGIYLNRQLY LTTLVYIPLA IPLWFCEYGF LYFGQDPFIS SQAAIYVRVC
IPGILFFTYG SCLGRFCSGH RETRFGMVSN IFSSIIHFFL AYLLAITLDL GMFGIAIASC
IHFFLRFLVY VVLIAKSERL RASLVSIWDP NCKNDLWPQF VLSLQCASLG IWSWWAFDIF
TLIASYMSVD DLAAQTVLRN IGLLTYMIPV GLSISSVILV GNMIGANNPN GAKLYAKMCT
LSAFIWALAS VAFINLLQGQ VIGIFSSSVS VNELILRAFN IISIFVFFDC VQGVGQGVIR
GLGKQGEASY VTIFGYWVLG IPISIDAVFY HSGGIVGLWI GPSVAIIFNF IFYYVLILRT
DWQKVCDEVQ ERRARDNKKL Q
//
