ID A0A078B778_STYLE Unreviewed; 1128 AA.
AC A0A078B778;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=ethanolamine-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00024221};
DE EC=2.7.7.14 {ECO:0000256|ARBA:ARBA00024221};
DE AltName: Full=CTP:phosphoethanolamine cytidylyltransferase {ECO:0000256|ARBA:ARBA00031473};
GN Name=Contig19091.g20242 {ECO:0000313|EMBL:CDW90365.1};
GN ORFNames=STYLEM_19507 {ECO:0000313|EMBL:CDW90365.1};
OS Stylonychia lemnae (Ciliate).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Stylonychia.
OX NCBI_TaxID=5949 {ECO:0000313|EMBL:CDW90365.1, ECO:0000313|Proteomes:UP000039865};
RN [1] {ECO:0000313|EMBL:CDW90365.1, ECO:0000313|Proteomes:UP000039865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=130c {ECO:0000313|EMBL:CDW90365.1,
RC ECO:0000313|Proteomes:UP000039865};
RA Swart Estienne;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.
CC {ECO:0000256|ARBA:ARBA00024191}.
CC -!- SIMILARITY: Belongs to the cytidylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010101}.
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DR EMBL; CCKQ01018404; CDW90365.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A078B778; -.
DR EnsemblProtists; CDW90365; CDW90365; STYLEM_19507.
DR InParanoid; A0A078B778; -.
DR OrthoDB; 5474784at2759; -.
DR UniPathway; UPA00558; UER00742.
DR Proteomes; UP000039865; Unassembled WGS sequence.
DR GO; GO:0004306; F:ethanolamine-phosphate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd02174; CCT; 1.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR InterPro; IPR041723; CCT.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR044608; Ect1/PCYT2.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 2.
DR PANTHER; PTHR45780; ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR45780:SF2; ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR Pfam; PF01467; CTP_transf_like; 2.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 2.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:CDW90365.1};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000039865};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CDW90365.1}.
FT DOMAIN 747..870
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT DOMAIN 964..1050
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT REGION 388..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1128 AA; 125620 MW; F8EC9B305B28CEF1 CRC64;
MLFFLIAYAQ NVQGQTSIQS QGASVTIYES FSNYVRDFFN SIFSSPAPSP QASNTTSNTN
STIIPQTPPI EKQNITKVMN QTTVLQNTTT STATIVEQQP INTNSSQNQT IITIREQINQ
TLQQSQVQFV NDSAQIISNL SKFNVLNFAN AVQQPQIIQI TLKTSILQIK VLNNSQINQT
LEVKQTNQTT TLDPNQTKVI IENNTNIIPG LNQSQPTGQN LTNISTLILN STNDLLITGQ
NSSTIPVITQ QQINSSTNQN VSSLEISLNQ TQNNNTATSN VITQNNTAII QNQEIIPQLN
QVNNSSNVSL PTNETTQSIN QNNQTQGTPA QVITYNTTIN ITKITINQTV PQQIDLNATN
SINSSNQNQS VQPMSLIQVN SAPFSAQNTL ISTNPNDQKR SSQSDKITDP LIKTQNQSNP
SIHIGDSVNV RVIENLNQVV IINQGQQPIQ IYQSSWSDSN VQPNNYSSMH NPQQSQPALG
VSQVSYTSGQ KSQSIQQVAS SPNTLTNKLN SEVNNSFSQM NDARMKQLNL LDSYLVLQAV
ELNCSTLCVF NCLYIATTMQ SKVTCMDTCL CFGNNTLDQS QNSQPVTAAP SIAKNISLIQ
LEKSHYKDQG MIAQTNTSGT KIPKLTEEVC FELLYFSKLT QLINNSEYMQ KVLSHLRDSF
SIEEGGQPST QSHDPNYLVL DAYHTATVSF KKLEALVRVD KGSDSDDAIQ EITDYVEKMH
NSKKSKSSQD LVALQSNLVK EPVRIYVDGG FDLIHSGHYN AIRQAKALGD ILVVGVNSDA
EILRNKGPTV LTCKERADIL RACKWVDEVH EDTEYTVRIE TLDRYNCQYY AHGDDPVFDA
DGTDMCGLLS QIGRFKMFKR TEGVSTTDIV GKLLLLTKDN SSKGRGRAGS FEKPMISTEY
VKEVRRIEKE EVKNENTNLS SLAPERQTAS AISIPTSHFL ATTRRIMHFS NNREPKATDR
VVYISGSFDL LHNGHIETLR KAKAQGDFLF VGVWPDETVN FFKGSNHPIL SLHERVLMVL
ACKYVDDVVV GAQYQITKDL IKSLNIQKVV QAKTKEDIIL EEHAHIDPNQ VAKEIGIFEE
FDIETDVTVE TIAQRVVENR EKYKAKYDKK IAQQDKYYAQ DKQYVAEL
//
