ID   A0A078B8D1_STYLE        Unreviewed;       561 AA.
AC   A0A078B8D1;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Voltage-gated chloride channel protein {ECO:0000313|EMBL:CDW90775.1};
GN   Name=Contig11496.g12306 {ECO:0000313|EMBL:CDW90775.1};
GN   ORFNames=STYLEM_19922 {ECO:0000313|EMBL:CDW90775.1};
OS   Stylonychia lemnae (Ciliate).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Stylonychia.
OX   NCBI_TaxID=5949 {ECO:0000313|EMBL:CDW90775.1, ECO:0000313|Proteomes:UP000039865};
RN   [1] {ECO:0000313|EMBL:CDW90775.1, ECO:0000313|Proteomes:UP000039865}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=130c {ECO:0000313|EMBL:CDW90775.1,
RC   ECO:0000313|Proteomes:UP000039865};
RA   Swart Estienne;
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CCKQ01018793; CDW90775.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A078B8D1; -.
DR   EnsemblProtists; CDW90775; CDW90775; STYLEM_19922.
DR   InParanoid; A0A078B8D1; -.
DR   OMA; WELINFA; -.
DR   OrthoDB; 206816at2759; -.
DR   Proteomes; UP000039865; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   PANTHER; PTHR45720; CHLORIDE CHANNEL PROTEIN 2; 1.
DR   PANTHER; PTHR45720:SF10; CHLORIDE CHANNEL PROTEIN 2; 1.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF81340; Clc chloride channel; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000039865};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        153..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        207..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        325..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        376..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        415..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        439..465
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   561 AA;  63541 MW;  35AE166C383900BF CRC64;
     MYELKDLNSL DVKLNFLQCG IDEFSQTSGI RRQLSGLRSK SRVKVRQHKL IKFKGIDVRA
     QQNDLFGNLK VSNFMFLVIL GASTALQQLI QQFSQEQTCT QRYVQLLDKI CMLDIVQLHL
     EYYSRDSEGS SLPEMKAVLA GVHISTFLSI RAFIGKLVGV TVAIVGGLSL GRYGSFVHMS
     GVIAHQMSYR IKFFQNIGSN YQLRLQVISA AIAAGTCCSA GSPFGGVIFA LELTSTYYMM
     GNMWKGLLCT TAAIITYSLM HQLPFVKPPK LTDFEEYTFN HEIIFFIILG YLCARVGALF
     IHILTKIIFL RGKLKNPLLL NRWKWCSIVI LFISIIQFPL RFLHFPERQV WNVMFNSHQI
     SEVQNGQVWS NPNLELVLLV YCILKFIFIV SSLTLPLPNG IFAPMISFGA VFGRLFDEGI
     YAVVGATCVY GSVTKTVSIA IIIFEVTGQI TLLVPVVIGL SVAYASSQAM TMSIFDVLLE
     FKNFPFLPTL GEGDTIHLKA RDIMNRNFVY LREDSEIREI RDILTQFEDF NYDPKNYIEY
     EELLSLEKKL QADLQEECSK V
//