ID A0A078F3X9_BRANA Unreviewed; 766 AA.
AC A0A078F3X9;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=acetyl-CoA carboxytransferase {ECO:0000256|ARBA:ARBA00011883};
DE EC=2.1.3.15 {ECO:0000256|ARBA:ARBA00011883};
GN Name=BnaA03g17570D {ECO:0000313|EMBL:CDY07754.1};
GN ORFNames=DARMORV10_A03P21030.1 {ECO:0000313|EMBL:CAF2123135.1},
GN GSBRNA2T00124881001 {ECO:0000313|EMBL:CDY07754.1};
OS Brassica napus (Rape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3708 {ECO:0000313|EMBL:CDY07754.1, ECO:0000313|Proteomes:UP000028999};
RN [1] {ECO:0000313|EMBL:CDY07754.1, ECO:0000313|Proteomes:UP000028999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Darmor-bzh {ECO:0000313|Proteomes:UP000028999};
RX PubMed=25146293; DOI=10.1126/science.1253435;
RA Chalhoub B., Denoeud F., Liu S., Parkin I.A., Tang H., Wang X., Chiquet J.,
RA Belcram H., Tong C., Samans B., Correa M., Da Silva C., Just J.,
RA Falentin C., Koh C.S., Le Clainche I., Bernard M., Bento P., Noel B.,
RA Labadie K., Alberti A., Charles M., Arnaud D., Guo H., Daviaud C.,
RA Alamery S., Jabbari K., Zhao M., Edger P.P., Chelaifa H., Tack D.,
RA Lassalle G., Mestiri I., Schnel N., Le Paslier M.C., Fan G., Renault V.,
RA Bayer P.E., Golicz A.A., Manoli S., Lee T.H., Thi V.H., Chalabi S., Hu Q.,
RA Fan C., Tollenaere R., Lu Y., Battail C., Shen J., Sidebottom C.H.,
RA Wang X., Canaguier A., Chauveau A., Berard A., Deniot G., Guan M., Liu Z.,
RA Sun F., Lim Y.P., Lyons E., Town C.D., Bancroft I., Wang X., Meng J.,
RA Ma J., Pires J.C., King G.J., Brunel D., Delourme R., Renard M., Aury J.M.,
RA Adams K.L., Batley J., Snowdon R.J., Tost J., Edwards D., Zhou Y., Hua W.,
RA Sharpe A.G., Paterson A.H., Guan C., Wincker P.;
RT "Plant genetics. Early allopolyploid evolution in the post-Neolithic
RT Brassica napus oilseed genome.";
RL Science 345:950-953(2014).
RN [2] {ECO:0000313|EMBL:CDY07754.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:CAF2123135.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope - CEA;
RA William W.;
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-
CC CoA + N(6)-biotinyl-L-lysyl-[protein]; Xref=Rhea:RHEA:54728,
CC Rhea:RHEA-COMP:10505, Rhea:RHEA-COMP:10506, ChEBI:CHEBI:57288,
CC ChEBI:CHEBI:57384, ChEBI:CHEBI:83144, ChEBI:CHEBI:83145; EC=2.1.3.15;
CC Evidence={ECO:0000256|ARBA:ARBA00001072};
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DR EMBL; HG994357; CAF2123135.1; -; Genomic_DNA.
DR EMBL; LK031980; CDY07754.1; -; Genomic_DNA.
DR STRING; 3708.A0A078F3X9; -.
DR PaxDb; 3708-A0A078F3X9; -.
DR EnsemblPlants; CDY07754; CDY07754; GSBRNA2T00124881001.
DR Gramene; CDY07754; CDY07754; GSBRNA2T00124881001.
DR OMA; FNNEITT; -.
DR UniPathway; UPA00655; UER00711.
DR Proteomes; UP000028999; Unassembled WGS sequence.
DR GO; GO:0009317; C:acetyl-CoA carboxylase complex; IEA:InterPro.
DR GO; GO:0003989; F:acetyl-CoA carboxylase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016743; F:carboxyl- or carbamoyltransferase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:2001295; P:malonyl-CoA biosynthetic process; IEA:UniProtKB-UniPathway.
DR HAMAP; MF_00823; AcetylCoA_CT_alpha; 1.
DR InterPro; IPR001095; Acetyl_CoA_COase_a_su.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR NCBIfam; TIGR00513; accA; 1.
DR NCBIfam; NF041504; AccA_sub; 1.
DR PANTHER; PTHR42853:SF4; ACETYL-COA CARBOXYTRANSFERASE; 1.
DR PANTHER; PTHR42853; ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT ALPHA; 1.
DR Pfam; PF03255; ACCA; 1.
DR PRINTS; PR01069; ACCCTRFRASEA.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR PROSITE; PS50989; COA_CT_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000028999}.
FT DOMAIN 127..381
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
FT REGION 730..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 421..476
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 739..755
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 766 AA; 85123 MW; 25033850CD10ADAE CRC64;
MASMSHSSIA LCGASASASD HLRSSTNGVS LRTLGRAMVA STKRSNLYVT ARLKKGKKFD
HPWPSNPDPN VKGGVLSYLS TFKPLGDTQK PVTLDFEKPL VELEKKIVDV RKMAAETGLD
FTDQIITLET KYRQALKDLY THLTPIQRVN IARHPNRPTF LDHIHNITDK FMELHGDRAG
YDDPAIVTGI GTIDGKRYMF IGHQKGRNTK ENIMRNFGMP TPHGYRKALR MMYYADHHGF
PIVTFIDTPG AYADLKSEEL GQGEAIANNL RTMFGLKVPI LSIVIGEGGS GGALAIGCAN
KMLMLENAVF YVASPEACAA ILWNSSKAAP EAAEKLRITS RELVKLNVAD GIIPEPLGGA
HADPSWTSQQ IKIAINENMN EFGKMNGDEL LKHRMAKYRK IGVFIENAPV EPEIKVNMKR
RDAVISNSRK LEGEVEKLRD QILKAKETSS EEAPSSEVLN EMIKKLKSEI DDEYTEAARA
MGLEERLTAM RGEFSKASAE EHLMHPILIE KIEKLKEEFN TRLSEAPNYE SLKSKLDMLK
DFSRAKAASE AASVKNEINK RFQEAVDRPE VREKVEAIKA EVASSGASSF EELSDELKEK
VLKTKGEVEA EMAGVLKSMG LELEAVKPNV AEQIFVPSEN IQEKVEKLNR EISEKIEEVV
RTPEIKSMVE LLRVENAKAS QTPGDTKVSS QKIETLEQQI KQKIADALSM SGLQEKQEEL
EKELAVAREL AAEKSQESLK EDDDDDDDDE DGSESEKPEI INPSFA
//
