ID A0A078GDS5_BRANA Unreviewed; 633 AA.
AC A0A078GDS5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=formate--tetrahydrofolate ligase {ECO:0000256|ARBA:ARBA00012295};
DE EC=6.3.4.3 {ECO:0000256|ARBA:ARBA00012295};
GN Name=BnaA06g02790D {ECO:0000313|EMBL:CDY22798.1};
GN ORFNames=DARMORV10_A06P03100.1 {ECO:0000313|EMBL:CAF2081522.1},
GN GSBRNA2T00021140001 {ECO:0000313|EMBL:CDY22798.1};
OS Brassica napus (Rape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3708 {ECO:0000313|EMBL:CDY22798.1, ECO:0000313|Proteomes:UP000028999};
RN [1] {ECO:0000313|EMBL:CDY22798.1, ECO:0000313|Proteomes:UP000028999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Darmor-bzh {ECO:0000313|Proteomes:UP000028999};
RX PubMed=25146293; DOI=10.1126/science.1253435;
RA Chalhoub B., Denoeud F., Liu S., Parkin I.A., Tang H., Wang X., Chiquet J.,
RA Belcram H., Tong C., Samans B., Correa M., Da Silva C., Just J.,
RA Falentin C., Koh C.S., Le Clainche I., Bernard M., Bento P., Noel B.,
RA Labadie K., Alberti A., Charles M., Arnaud D., Guo H., Daviaud C.,
RA Alamery S., Jabbari K., Zhao M., Edger P.P., Chelaifa H., Tack D.,
RA Lassalle G., Mestiri I., Schnel N., Le Paslier M.C., Fan G., Renault V.,
RA Bayer P.E., Golicz A.A., Manoli S., Lee T.H., Thi V.H., Chalabi S., Hu Q.,
RA Fan C., Tollenaere R., Lu Y., Battail C., Shen J., Sidebottom C.H.,
RA Wang X., Canaguier A., Chauveau A., Berard A., Deniot G., Guan M., Liu Z.,
RA Sun F., Lim Y.P., Lyons E., Town C.D., Bancroft I., Wang X., Meng J.,
RA Ma J., Pires J.C., King G.J., Brunel D., Delourme R., Renard M., Aury J.M.,
RA Adams K.L., Batley J., Snowdon R.J., Tost J., Edwards D., Zhou Y., Hua W.,
RA Sharpe A.G., Paterson A.H., Guan C., Wincker P.;
RT "Plant genetics. Early allopolyploid evolution in the post-Neolithic
RT Brassica napus oilseed genome.";
RL Science 345:950-953(2014).
RN [2] {ECO:0000313|EMBL:CDY22798.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:CAF2081522.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope - CEA;
RA William W.;
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion.
CC {ECO:0000256|ARBA:ARBA00004777}.
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DR EMBL; HG994360; CAF2081522.1; -; Genomic_DNA.
DR EMBL; LK032136; CDY22798.1; -; Genomic_DNA.
DR STRING; 3708.A0A078GDS5; -.
DR PaxDb; 3708-A0A078GDS5; -.
DR EnsemblPlants; CDY22798; CDY22798; GSBRNA2T00021140001.
DR Gramene; CDY22798; CDY22798; GSBRNA2T00021140001.
DR OMA; REDHFVI; -.
DR UniPathway; UPA00193; -.
DR Proteomes; UP000028999; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
DR CDD; cd00477; FTHFS; 1.
DR Gene3D; 1.10.8.770; -; 1.
DR Gene3D; 3.10.410.10; Formyltetrahydrofolate synthetase, domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01543; FTHFS; 1.
DR InterPro; IPR000559; Formate_THF_ligase.
DR InterPro; IPR020628; Formate_THF_ligase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF01268; FTHFS; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00721; FTHFS_1; 1.
DR PROSITE; PS00722; FTHFS_2; 1.
PE 3: Inferred from homology;
KW One-carbon metabolism {ECO:0000256|ARBA:ARBA00022563};
KW Reference proteome {ECO:0000313|Proteomes:UP000028999}.
SQ SEQUENCE 633 AA; 67809 MW; D2F5098034FC3D78 CRC64;
MSSSRKLQVV SPVPADIDIA NSVEPLHIAE IAKDLNLSPL HYDLYGKYKA KVLLSAFDEL
KDREDGYYVV VGGITPTPLG EGKSTTTVGL CQALGAYLDK KVVTCLRQPS QGPTFGIKGG
AAGGGYSQVI PMDEFNLHLT GDIHAITASN NLLAAAIDTR IFHEASQSDK ALFNRLCPVN
KEGKRSFSDI MFRRLNKLGI SKTIPEELTT EEVKKFARLD IDPDSITWRR VMDVNDRFLR
KITVGQGPEE KGMTRETGFD ISVASEIMAV LALTTSLGDM RERLGKMVIG NSKAGEPITA
DDLGVGGALT VLMKDAIHPT LMQTLEGTPV LVHAGPFANI AHGNSSIVAD KIALKLVGPG
GFVVTEAGFG SDIGTEKFMN IKCRYSGLTP QCAIVVATVR ALKMHGGGPD VVAGRPLDRA
YVSENVSLVE AGCVNLAKHI ANTKAYGVNV VVAVNMFSTD SEAELNAVRK FSMEAGAFDA
VICSHHAHGG KGAVDLGIAV EKACQNITQP LRFLYPLEIS IKDKIEAIAK SYGASGVEYS
DQAEKQIEMY TQQGFSNLPI CMSKTQYSFS HDASKKGAPT GFVLPIRDVR GSIGAGFIYP
LVGTMSTMPG LPTRPCFYEI DIDTVTGKVR GLS
//
