ID A0A078HBZ3_BRANA Unreviewed; 1121 AA.
AC A0A078HBZ3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=BnaC03g59310D {ECO:0000313|EMBL:CDY35292.1};
GN ORFNames=GSBRNA2T00058238001 {ECO:0000313|EMBL:CDY35292.1};
OS Brassica napus (Rape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3708 {ECO:0000313|EMBL:CDY35292.1, ECO:0000313|Proteomes:UP000028999};
RN [1] {ECO:0000313|EMBL:CDY35292.1, ECO:0000313|Proteomes:UP000028999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Darmor-bzh {ECO:0000313|Proteomes:UP000028999};
RX PubMed=25146293; DOI=10.1126/science.1253435;
RA Chalhoub B., Denoeud F., Liu S., Parkin I.A., Tang H., Wang X., Chiquet J.,
RA Belcram H., Tong C., Samans B., Correa M., Da Silva C., Just J.,
RA Falentin C., Koh C.S., Le Clainche I., Bernard M., Bento P., Noel B.,
RA Labadie K., Alberti A., Charles M., Arnaud D., Guo H., Daviaud C.,
RA Alamery S., Jabbari K., Zhao M., Edger P.P., Chelaifa H., Tack D.,
RA Lassalle G., Mestiri I., Schnel N., Le Paslier M.C., Fan G., Renault V.,
RA Bayer P.E., Golicz A.A., Manoli S., Lee T.H., Thi V.H., Chalabi S., Hu Q.,
RA Fan C., Tollenaere R., Lu Y., Battail C., Shen J., Sidebottom C.H.,
RA Wang X., Canaguier A., Chauveau A., Berard A., Deniot G., Guan M., Liu Z.,
RA Sun F., Lim Y.P., Lyons E., Town C.D., Bancroft I., Wang X., Meng J.,
RA Ma J., Pires J.C., King G.J., Brunel D., Delourme R., Renard M., Aury J.M.,
RA Adams K.L., Batley J., Snowdon R.J., Tost J., Edwards D., Zhou Y., Hua W.,
RA Sharpe A.G., Paterson A.H., Guan C., Wincker P.;
RT "Plant genetics. Early allopolyploid evolution in the post-Neolithic
RT Brassica napus oilseed genome.";
RL Science 345:950-953(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; LK032349; CDY35292.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A078HBZ3; -.
DR PaxDb; 3708-A0A078HBZ3; -.
DR EnsemblPlants; CDY35292; CDY35292; GSBRNA2T00058238001.
DR Gramene; CDY35292; CDY35292; GSBRNA2T00058238001.
DR OMA; SSTMSEW; -.
DR Proteomes; UP000028999; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IBA:GO_Central.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 2.60.120.430; Galactose-binding lectin; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR021720; Malectin_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48006; LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED; 1.
DR PANTHER; PTHR48006:SF66; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 2.
DR Pfam; PF11721; Malectin; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000028999};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1121
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001736759"
FT TRANSMEM 588..608
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1072..1090
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1096..1115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 644..917
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 672
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1121 AA; 124390 MW; 634F839FB2F7AEF8 CRC64;
MWVVFWALLL FFIIITSFFA TLTTSASPAL HADELHALGE ITTTLGIKRL NLSDGDPCFL
KTLKLGGGVS NVVNMPVNNI VCDCSFNNNM TCHITEIFLK STSLPGKLPP ELAKLRYLQK
IDLCRNYLSG SIPMEWASMP HLTFISLCAN NLSGPLPPGL QNFKNLTFLG VEANQFSGHI
PDEFGNLTSL TGLELASNQF TGSLPSSLAR LVNLEIFRIS DNNFSGIIPE YIGNWSRLQR
LDLQASGLKG PIPDAVARLE NLTNLIISDM TGINSFPNIS SQVIQNLILR NVSMSGPIPS
YIWSKPVLRS LDLSFNKLTG EVLGINLVPK LTYLTGNMLS GEIKSGVYLN SKSNIDLSYN
NFSWPSSCQE RSNINTYRSS YLKNILNGLL PCAGPVTCKR YKRSLHINCG GETVTVTNSI
GKITYQADNS DQVKAATNQH FKNWGISNTG DFMDDNIDDD TYIISTSLTL PGDSPDLYKT
ARRSALSLVY YAFCLENGEY NLKLHFMEIQ FSDQELYSRL GRRIFDVYVQ GKLFLRDFNI
RQEANGTLKS IVKELKAVNV TDHKLEIWLY WAGKGTTLIP KRGNYGPLIS AISLCHTIIF
LALGFYAHRK FRQDKKKRER DLRARGLQTV CFTWRQLQAA TNDFDEANKL GEGGFGSVFK
GELPDGTIIA VKQLSSKSCQ GNREFVNEIG MISGLNHPNL VKLYGCCVEK DQLLLVYEYM
ENNSLALVLS GKSSMKLDWK ARQKICVGIA RGLEFLHEGS MITMVHRDIK TPNVLLDADL
NAKISDFGLA RLHEEEHTHI STKVAGTMGY MAPEYVLWGQ LTEKADVYSF GVVAMEIVSG
KSNTKHKGTA DHISLLDWAL SLHQKGNILE VVDPVLEGHF NRKEAVRMIN VALVCTNSSP
ALRPTMSEAV KMLEGVIELT QVSSDPGIYG DDWSLLKLRD IDDTHGSSST SVHALEEIAI
TLGIKRVNLS YKDPCGSRSL MVIKQVDWNP EVNNTIACDC SFNNNMTCHI TELTLVNLTL
VGKVPPELAK LRHLRSTNIT KVSYEFFSLT CSDLSANYLT GTIPPEWVSM PYLTFMLAPS
LCLTLMLHLH DLRITLNILA AGSAGIVCLG IYQLGCKTSR I
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