ID A0A078HC74_BRANA Unreviewed; 423 AA.
AC A0A078HC74;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Defective in cullin neddylation protein {ECO:0000256|RuleBase:RU410713};
GN Name=BnaA06g10540D {ECO:0000313|EMBL:CDY35044.1};
GN ORFNames=DARMORV10_A06P11910.1 {ECO:0000313|EMBL:CAF2083407.1},
GN GSBRNA2T00057909001 {ECO:0000313|EMBL:CDY35044.1};
OS Brassica napus (Rape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3708 {ECO:0000313|EMBL:CDY35044.1, ECO:0000313|Proteomes:UP000028999};
RN [1] {ECO:0000313|EMBL:CDY35044.1, ECO:0000313|Proteomes:UP000028999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Darmor-bzh {ECO:0000313|Proteomes:UP000028999};
RX PubMed=25146293; DOI=10.1126/science.1253435;
RA Chalhoub B., Denoeud F., Liu S., Parkin I.A., Tang H., Wang X., Chiquet J.,
RA Belcram H., Tong C., Samans B., Correa M., Da Silva C., Just J.,
RA Falentin C., Koh C.S., Le Clainche I., Bernard M., Bento P., Noel B.,
RA Labadie K., Alberti A., Charles M., Arnaud D., Guo H., Daviaud C.,
RA Alamery S., Jabbari K., Zhao M., Edger P.P., Chelaifa H., Tack D.,
RA Lassalle G., Mestiri I., Schnel N., Le Paslier M.C., Fan G., Renault V.,
RA Bayer P.E., Golicz A.A., Manoli S., Lee T.H., Thi V.H., Chalabi S., Hu Q.,
RA Fan C., Tollenaere R., Lu Y., Battail C., Shen J., Sidebottom C.H.,
RA Wang X., Canaguier A., Chauveau A., Berard A., Deniot G., Guan M., Liu Z.,
RA Sun F., Lim Y.P., Lyons E., Town C.D., Bancroft I., Wang X., Meng J.,
RA Ma J., Pires J.C., King G.J., Brunel D., Delourme R., Renard M., Aury J.M.,
RA Adams K.L., Batley J., Snowdon R.J., Tost J., Edwards D., Zhou Y., Hua W.,
RA Sharpe A.G., Paterson A.H., Guan C., Wincker P.;
RT "Plant genetics. Early allopolyploid evolution in the post-Neolithic
RT Brassica napus oilseed genome.";
RL Science 345:950-953(2014).
RN [2] {ECO:0000313|EMBL:CDY35044.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:CAF2083407.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope - CEA;
RA William W.;
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Neddylation of cullins play an essential role in the
CC regulation of SCF-type complexes activity.
CC {ECO:0000256|RuleBase:RU410713}.
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DR EMBL; HG994360; CAF2083407.1; -; Genomic_DNA.
DR EMBL; LK032346; CDY35044.1; -; Genomic_DNA.
DR STRING; 3708.A0A078HC74; -.
DR PaxDb; 3708-A0A078HC74; -.
DR EnsemblPlants; CDY35044; CDY35044; GSBRNA2T00057909001.
DR Gramene; CDY35044; CDY35044; GSBRNA2T00057909001.
DR OMA; CENGCKM; -.
DR Proteomes; UP000028999; Unassembled WGS sequence.
DR GO; GO:0000151; C:ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0097602; F:cullin family protein binding; IBA:GO_Central.
DR GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:GO_Central.
DR GO; GO:0032182; F:ubiquitin-like protein binding; IBA:GO_Central.
DR GO; GO:0045116; P:protein neddylation; IBA:GO_Central.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 1.10.238.200; Cullin, PONY binding domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR014764; DCN-prot.
DR InterPro; IPR042460; DCN1-like_PONY.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR005176; PONY_dom.
DR PANTHER; PTHR12281:SF35; DEFECTIVE IN CULLIN NEDDYLATION PROTEIN; 1.
DR PANTHER; PTHR12281; RP42 RELATED; 1.
DR Pfam; PF03556; Cullin_binding; 1.
DR Pfam; PF14709; DND1_DSRM; 1.
DR SMART; SM00358; DSRM; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS51229; DCUN1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028999}.
FT DOMAIN 228..419
FT /note="DCUN1"
FT /evidence="ECO:0000259|PROSITE:PS51229"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 423 AA; 48920 MW; 30723462223EAF43 CRC64;
MYLPPEDPSS PVPNASSMTP KPRMMIQRCE NGCKMRKLND DVEEDNDSSK MESNITHVEA
ENKLPVVSEP EAAAALVPHA TKPETTEEEA QKVCAREQLY KLCGVRHWKA PLYTFFNQDG
PDNTKLFKVE VSVEIKEVSG ITVLECLGDP HNKKKIAAEQ AAEVALWFLK NHLYETDVNE
RAFEMFKAQR SNKVMRRSAA ASSKKKSDSI TSSTTDLFRS ASSKATTKEM DRIDHLFNQY
ANTSSNLIDP EGIEELCSNL EVPHTDIRIL MLAWKMKSEK QGYFTQEEWR RGLKALRADT
LNKLKKALPE LEKEVRRQSN FADFYAYAFR YCLTEEKQKS IDIETICQLL EIVMGSTFRP
QVDYFVEYLK IQNDYKVINM DQWMGFYRFC NEISFPEMTE YNPELAWPLV LDNFVEWIRE
KQA
//
