ID A0A078J6L5_BRANA Unreviewed; 402 AA.
AC A0A078J6L5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=formate--tetrahydrofolate ligase {ECO:0000256|ARBA:ARBA00012295};
DE EC=6.3.4.3 {ECO:0000256|ARBA:ARBA00012295};
GN Name=BnaC05g51210D {ECO:0000313|EMBL:CDY62106.1};
GN ORFNames=GSBRNA2T00035964001 {ECO:0000313|EMBL:CDY62106.1};
OS Brassica napus (Rape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3708 {ECO:0000313|EMBL:CDY62106.1, ECO:0000313|Proteomes:UP000028999};
RN [1] {ECO:0000313|EMBL:CDY62106.1, ECO:0000313|Proteomes:UP000028999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Darmor-bzh {ECO:0000313|Proteomes:UP000028999};
RX PubMed=25146293; DOI=10.1126/science.1253435;
RA Chalhoub B., Denoeud F., Liu S., Parkin I.A., Tang H., Wang X., Chiquet J.,
RA Belcram H., Tong C., Samans B., Correa M., Da Silva C., Just J.,
RA Falentin C., Koh C.S., Le Clainche I., Bernard M., Bento P., Noel B.,
RA Labadie K., Alberti A., Charles M., Arnaud D., Guo H., Daviaud C.,
RA Alamery S., Jabbari K., Zhao M., Edger P.P., Chelaifa H., Tack D.,
RA Lassalle G., Mestiri I., Schnel N., Le Paslier M.C., Fan G., Renault V.,
RA Bayer P.E., Golicz A.A., Manoli S., Lee T.H., Thi V.H., Chalabi S., Hu Q.,
RA Fan C., Tollenaere R., Lu Y., Battail C., Shen J., Sidebottom C.H.,
RA Wang X., Canaguier A., Chauveau A., Berard A., Deniot G., Guan M., Liu Z.,
RA Sun F., Lim Y.P., Lyons E., Town C.D., Bancroft I., Wang X., Meng J.,
RA Ma J., Pires J.C., King G.J., Brunel D., Delourme R., Renard M., Aury J.M.,
RA Adams K.L., Batley J., Snowdon R.J., Tost J., Edwards D., Zhou Y., Hua W.,
RA Sharpe A.G., Paterson A.H., Guan C., Wincker P.;
RT "Plant genetics. Early allopolyploid evolution in the post-Neolithic
RT Brassica napus oilseed genome.";
RL Science 345:950-953(2014).
CC -!- PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion.
CC {ECO:0000256|ARBA:ARBA00004777}.
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DR EMBL; LK034100; CDY62106.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A078J6L5; -.
DR STRING; 3708.A0A078J6L5; -.
DR PaxDb; 3708-A0A078J6L5; -.
DR EnsemblPlants; CDY62106; CDY62106; GSBRNA2T00035964001.
DR Gramene; CDY62106; CDY62106; GSBRNA2T00035964001.
DR UniPathway; UPA00193; -.
DR Proteomes; UP000028999; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.1510.10; Domain 2, N(10)-formyltetrahydrofolate synthetase; 1.
DR Gene3D; 3.10.410.10; Formyltetrahydrofolate synthetase, domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000559; Formate_THF_ligase.
DR InterPro; IPR020628; Formate_THF_ligase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF01268; FTHFS; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00722; FTHFS_2; 1.
PE 4: Predicted;
KW One-carbon metabolism {ECO:0000256|ARBA:ARBA00022563};
KW Reference proteome {ECO:0000313|Proteomes:UP000028999}.
SQ SEQUENCE 402 AA; 42518 MW; 28D9650E071C1327 CRC64;
MDVNDRFLRK MTVGQGSEEK GMIRETGFDI SVASEIMAVL ALTTSLDDMR ERLGTMVIGN
SRAGEPITAD DLGVGGALTV LMKDAIHPTL MQTLEGTPVL VHAGPFANIA HGNSSIVADK
IALKLVGPGG FVVTEAGFGS DIGTEKFMNI KCRYSGLRPQ CAVVVATVRA LKMHGGGPGV
VAGRPLDHAY VSENVSLVEA GCVNLAKHIS NIKAYGVNVV VAVNVFSTDT EAELNAVRKF
SMDAGAFDAV ICSHHAHGGK GAVDLGIAVE RACQNITQPL KFLYPLDISI KEKIEAIAKS
YGASGVEYSD QAEKQIEMYT QQGFSNLPIC MSKTQYSFSH DASKKGAPSG FVLPVRDVRG
SIGAGFIYPL VGTMSTMPGL PTRPCFYEID IDTVTGKVVG LS
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