ID A0A078JA01_BRANA Unreviewed; 907 AA.
AC A0A078JA01;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Lipoxygenase {ECO:0000256|RuleBase:RU003975};
DE EC=1.13.11.- {ECO:0000256|RuleBase:RU003975};
GN Name=BnaA01g36630D {ECO:0000313|EMBL:CDY64191.1};
GN ORFNames=GSBRNA2T00040971001 {ECO:0000313|EMBL:CDY64191.1};
OS Brassica napus (Rape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3708 {ECO:0000313|EMBL:CDY64191.1, ECO:0000313|Proteomes:UP000028999};
RN [1] {ECO:0000313|EMBL:CDY64191.1, ECO:0000313|Proteomes:UP000028999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Darmor-bzh {ECO:0000313|Proteomes:UP000028999};
RX PubMed=25146293; DOI=10.1126/science.1253435;
RA Chalhoub B., Denoeud F., Liu S., Parkin I.A., Tang H., Wang X., Chiquet J.,
RA Belcram H., Tong C., Samans B., Correa M., Da Silva C., Just J.,
RA Falentin C., Koh C.S., Le Clainche I., Bernard M., Bento P., Noel B.,
RA Labadie K., Alberti A., Charles M., Arnaud D., Guo H., Daviaud C.,
RA Alamery S., Jabbari K., Zhao M., Edger P.P., Chelaifa H., Tack D.,
RA Lassalle G., Mestiri I., Schnel N., Le Paslier M.C., Fan G., Renault V.,
RA Bayer P.E., Golicz A.A., Manoli S., Lee T.H., Thi V.H., Chalabi S., Hu Q.,
RA Fan C., Tollenaere R., Lu Y., Battail C., Shen J., Sidebottom C.H.,
RA Wang X., Canaguier A., Chauveau A., Berard A., Deniot G., Guan M., Liu Z.,
RA Sun F., Lim Y.P., Lyons E., Town C.D., Bancroft I., Wang X., Meng J.,
RA Ma J., Pires J.C., King G.J., Brunel D., Delourme R., Renard M., Aury J.M.,
RA Adams K.L., Batley J., Snowdon R.J., Tost J., Edwards D., Zhou Y., Hua W.,
RA Sharpe A.G., Paterson A.H., Guan C., Wincker P.;
RT "Plant genetics. Early allopolyploid evolution in the post-Neolithic
RT Brassica napus oilseed genome.";
RL Science 345:950-953(2014).
CC -!- FUNCTION: Plant lipoxygenase may be involved in a number of diverse
CC aspects of plant physiology including growth and development, pest
CC resistance, and senescence or responses to wounding.
CC {ECO:0000256|RuleBase:RU003975}.
CC -!- PATHWAY: Lipid metabolism; oxylipin biosynthesis.
CC {ECO:0000256|RuleBase:RU003975}.
CC -!- SIMILARITY: Belongs to the lipoxygenase family.
CC {ECO:0000256|ARBA:ARBA00009419, ECO:0000256|RuleBase:RU003975}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; LK034416; CDY64191.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A078JA01; -.
DR STRING; 3708.A0A078JA01; -.
DR PaxDb; 3708-A0A078JA01; -.
DR EnsemblPlants; CDY64191; CDY64191; GSBRNA2T00040971001.
DR Gramene; CDY64191; CDY64191; GSBRNA2T00040971001.
DR OMA; WWTELRN; -.
DR UniPathway; UPA00382; -.
DR Proteomes; UP000028999; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IBA:GO_Central.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0034440; P:lipid oxidation; IBA:GO_Central.
DR GO; GO:0031408; P:oxylipin biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd01751; PLAT_LH2; 1.
DR Gene3D; 3.10.450.60; -; 1.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR InterPro; IPR000907; LipOase.
DR InterPro; IPR013819; LipOase_C.
DR InterPro; IPR036226; LipOase_C_sf.
DR InterPro; IPR020834; LipOase_CS.
DR InterPro; IPR001246; LipOase_plant.
DR InterPro; IPR042057; Lipoxy_PLAT/LH2.
DR InterPro; IPR027433; Lipoxygenase_dom_3.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR PANTHER; PTHR11771:SF112; LINOLEATE 9S-LIPOXYGENASE 5; 1.
DR PANTHER; PTHR11771; LIPOXYGENASE; 1.
DR Pfam; PF00305; Lipoxygenase; 1.
DR Pfam; PF01477; PLAT; 1.
DR PRINTS; PR00087; LIPOXYGENASE.
DR PRINTS; PR00468; PLTLPOXGNASE.
DR SMART; SM00308; LH2; 1.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR SUPFAM; SSF48484; Lipoxigenase; 1.
DR PROSITE; PS00081; LIPOXYGENASE_2; 1.
DR PROSITE; PS51393; LIPOXYGENASE_3; 1.
DR PROSITE; PS50095; PLAT; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160,
KW ECO:0000256|RuleBase:RU003975};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516,
KW ECO:0000256|RuleBase:RU003975};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Oxylipin biosynthesis {ECO:0000256|ARBA:ARBA00022767,
KW ECO:0000256|RuleBase:RU003975};
KW Reference proteome {ECO:0000313|Proteomes:UP000028999}.
FT DOMAIN 52..197
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 200..907
FT /note="Lipoxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51393"
FT REGION 252..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 907 AA; 103920 MW; 1843CA1001B6E62A CRC64;
MIHTHIAEIL CVKPKTKKTK KTKTMEEDVK NKKTKKTMKI EGEIVVMKKN LLDFKDTMAS
LLDRIHELLG RRVSLHLISS LQPDLGIRSF FYSTRLHTYP NEKRGRLGKA AHLEKWVTKI
KTSVTAEETA FGVTFDWDES MGPPAAFVIK NHHRSQFYLK SLTLRNFPGG EGGAIHFVCN
SWIYPSHRYR CDRVFFSNQA YLPSETPELV KELREQELKN LRGEEKGGEL KEWDRVYDYA
YYNDLGAPDK GPDSARPVLG GSLEFPYPRR GKTGRKPTKS DPKSESRLAL LNLNIYVPRD
ERFSHVKFSD FLAYALKSVT QVLVPEIASL CDKTINEFDS FEDVFHLYDG SIKLANGHTI
SKLRDIIPWE MFRELVRNDG ERFMKFPLPD VLKQSRSAWR TDEEFAREML AGLNPVVISR
LKDFPPKSNL DSAKYGNQNS SIREEHIEPH MNGTSVQEAL EQNKLFILDH HDALMPYLTR
INSTNTKTYA TRTLLLLQED GTLKPLAIEL SLPHAQGESH GSVSKIFTPS EKGVEGTIWQ
LAKAYAAVND SGYHQLISHW YVFELQTHAV IEPFIIASNR QLSVVHPIYK LLHPHFRDTM
NINALARHVL INSDGVLERT VFPSRYAMEM SSSIYKSWVF TDQALPKDLL KRGVAVEDPS
SDNGVKLLIE DYPFAVDGLE IWSAIKTWVT EYCSFYYKND RTVQTDTEIQ SWWTELRTEG
HGDIQHESWW PSMQTRDDLI ETCTIIIWIA SALHAAVNFG QYPYAGFLPN RPTVSRRFMP
EPGTKEYTEL EESEEVAFLK TITPQLQTLL GISIIEILSM HSTDEIYLGQ RDSPNWTADD
EPLEAFKRFG KSLEVIENNI IRRNNDKRLK NRTGPVNIPY TLLYPNTTDY TREGGLTGKG
IPNSVSI
//
