ID A0A078KAT3_9GAMM Unreviewed; 440 AA.
AC A0A078KAT3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA repair protein RadA {ECO:0000256|RuleBase:RU003555};
GN Name=radA {ECO:0000313|EMBL:CDZ16291.1};
GN ORFNames=CEM_018 {ECO:0000313|EMBL:CDZ16291.1};
OS Candidatus Evansia muelleri.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Zymobacter group; Evansia.
OX NCBI_TaxID=1495769 {ECO:0000313|EMBL:CDZ16291.1, ECO:0000313|Proteomes:UP000032420};
RN [1] {ECO:0000313|Proteomes:UP000032420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Santos-Garcia D.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent ATPase involved in processing of recombination
CC intermediates, plays a role in repairing DNA breaks. Stimulates the
CC branch migration of RecA-mediated strand transfer reactions, allowing
CC the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA
CC in the presence of ADP but not other nucleotides, has ATPase activity
CC that is stimulated by ssDNA and various branched DNA structures, but
CC inhibited by SSB. Does not have RecA's homology-searching function.
CC {ECO:0000256|RuleBase:RU003555}.
CC -!- SIMILARITY: Belongs to the RecA family. RadA subfamily.
CC {ECO:0000256|RuleBase:RU003555}.
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DR EMBL; LM655252; CDZ16291.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A078KAT3; -.
DR STRING; 1495769.CEM_018; -.
DR KEGG; eme:CEM_018; -.
DR PATRIC; fig|1495769.3.peg.13; -.
DR HOGENOM; CLU_018264_0_0_6; -.
DR Proteomes; UP000032420; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR004504; DNA_repair_RadA.
DR InterPro; IPR014774; KaiC-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00416; sms; 1.
DR PANTHER; PTHR32472; DNA REPAIR PROTEIN RADA; 1.
DR PANTHER; PTHR32472:SF10; DNA REPAIR PROTEIN RADA-LIKE PROTEIN; 1.
DR Pfam; PF06745; ATPase; 1.
DR Pfam; PF13541; ChlI; 1.
DR PRINTS; PR01874; DNAREPAIRADA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003555};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003555};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003555};
KW DNA-binding {ECO:0000256|RuleBase:RU003555};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Ligase {ECO:0000313|EMBL:CDZ16291.1};
KW Metal-binding {ECO:0000256|RuleBase:RU003555};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003555};
KW Reference proteome {ECO:0000313|Proteomes:UP000032420};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Zinc {ECO:0000256|RuleBase:RU003555};
KW Zinc-finger {ECO:0000256|RuleBase:RU003555}.
FT DOMAIN 56..205
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
SQ SEQUENCE 440 AA; 49623 MW; 0781A273053B60DC CRC64;
MIKKNYICYE CNTKYTKWLG KCINCLQWNK ILEYKSSYYK NTLNKIIDIS TINLNKVNKI
SSKFEEFDRV LGGGFIPGST ILLGGNPGTG KSTLFLQIAN KLIIQNLKVL YITGEETLLQ
LAFRANRLFI NKGIKLLQET SVTKIIDIIE CNPMDIVIID SIQTMIVENI NKYLTGGVIQ
IRQSAYILIN FAKKKGIVLL LIGHVIKDGN LAGPKLLEHM IDVSLMLETN QDYRMLRSTK
NRFGSINELG IFKMLESGMK EVKDPSSIFI SQNKENTPGN VVMIILEGTR PILVEIQALV
EEHNKLINYK MISVGIDINR LSLLITILNK YTGLFIGNIF INVVGGIKII ETSADLAVLA
VIISSLHNRY IPMEFVILGE VGLNGEIRPI INIENRLLEA IKHGFTKAII PKNNIKSNFD
FKKITIFCIE KISELLKIIL
//
