ID A0A078KNF2_9FIRM Unreviewed; 882 AA.
AC A0A078KNF2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Small GTP-binding domain protein {ECO:0000313|EMBL:CDZ24003.1};
GN ORFNames=CCDG5_0878 {ECO:0000313|EMBL:CDZ24003.1};
OS [Clostridium] cellulosi.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Oscillospiraceae incertae sedis.
OX NCBI_TaxID=29343 {ECO:0000313|EMBL:CDZ24003.1, ECO:0000313|Proteomes:UP000032431};
RN [1] {ECO:0000313|Proteomes:UP000032431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG5 {ECO:0000313|Proteomes:UP000032431};
RA Wibberg D.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Abolishes the inhibitory effect of tetracyclin on protein
CC synthesis by a non-covalent modification of the ribosomes.
CC {ECO:0000256|ARBA:ARBA00003987}.
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DR EMBL; LM995447; CDZ24003.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A078KNF2; -.
DR STRING; 29343.CCDG5_0878; -.
DR KEGG; ccel:CCDG5_0878; -.
DR PATRIC; fig|29343.3.peg.936; -.
DR HOGENOM; CLU_002794_5_0_9; -.
DR OrthoDB; 9801472at2; -.
DR Proteomes; UP000032431; Chromosome.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
DR CDD; cd10912; PIN_YacP-like; 1.
DR CDD; cd03711; Tet_C; 1.
DR CDD; cd01684; Tet_like_IV; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR035650; Tet_C.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR InterPro; IPR010298; YacP-like.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF1; RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF05991; NYN_YacP; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR PRINTS; PR01037; TCRTETOQM.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000032431}.
FT DOMAIN 1..227
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT COILED 830..857
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 882 AA; 100467 MW; 07D5B04377CBA3D8 CRC64;
MKKLVIGILA HVDAGKTTLS EGMLYLSGKI RKLGRVDNKD SYLDTYELER QRGITIFSKQ
AIFEVDDTQI TLLDTPGHVD FSAETERTLQ VLDYAVLVVS GADGVQGHTK TLWRLLEMYN
IPVFIFINKM DQNGTDKDKL LREIKERMSN RCVEFEQINT TAFFEEIAMC DEELMDTYLE
TGHIDTALIK KAIKKRKIYP CLFGSALKLE GVERLLHTVV EYTDEPSYPA EFGAKIFKIS
RDSQGNRLTH LKVTGGKLKV KDILSGDSWK EKIDQIRIYS GEKFKTVNEI EAGGVCAVTG
LSNSRPGEGL GIEKASNKPV LEPVLSYRII LPDGMDPRAM LPKLRQIEEE EPELHIVWDE
RLQEIKVQVM GEVQTEILQS VIKNRFGVDV AFGEGKIVYK ETIANAVEGV GHFEPLRHYA
EVHLLLEPGE PGSGLQFDTI CSEDLLSRNW QRLILTHLKE KEHKGVLTGS AITDMKITLV
SGKASNKHTE GGDFREATYR AVRQGLKEAE SILLEPVYAF QLELPKKMVG RAMSDIENMH
GTYKISQTDG ETVVLTGTAP VITMRNYQKE VAAYTGGLGR LFCSLKGYEP CHNAEEVIES
IGYDSERDME NPTGSVFCAH GAGFLVDWYE VKNYMHLPSY FQDKTESEDE VVKHRTQKEE
MNISPEEVDE ILKRTSYANQ RDKEKIKQKP KRESYSGPIN RVSIKKENKE EYLLVDGYNI
IHAWPELKDL ADENMDGARM KLIETLSNYQ GYRKCQIIVV FDAYRVERHV EEAIDFNNIH
IIYTREAQTA DQYIERFSHN NKKKYSITVA TSDALEQLIV RGAGCSLLSA NELKAEIEKT
DRRIRQEYRQ INDENRNYLK DTLPSKTKRE MEEMINKGRG VK
//
