ID A0A078KRC2_9FIRM Unreviewed; 416 AA.
AC A0A078KRC2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Permease {ECO:0000313|EMBL:CDZ25067.1};
GN ORFNames=CCDG5_1975 {ECO:0000313|EMBL:CDZ25067.1};
OS [Clostridium] cellulosi.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Oscillospiraceae incertae sedis.
OX NCBI_TaxID=29343 {ECO:0000313|EMBL:CDZ25067.1, ECO:0000313|Proteomes:UP000032431};
RN [1] {ECO:0000313|Proteomes:UP000032431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG5 {ECO:0000313|Proteomes:UP000032431};
RA Wibberg D.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LM995447; CDZ25067.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A078KRC2; -.
DR STRING; 29343.CCDG5_1975; -.
DR KEGG; ccel:CCDG5_1975; -.
DR PATRIC; fig|29343.3.peg.2076; -.
DR HOGENOM; CLU_034180_11_2_9; -.
DR OrthoDB; 9763297at2; -.
DR Proteomes; UP000032431; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06173; MFS_MefA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR010290; TM_effector.
DR PANTHER; PTHR23513; INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR PANTHER; PTHR23513:SF11; STAPHYLOFERRIN A TRANSPORTER; 1.
DR Pfam; PF05977; MFS_3; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032431};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 26..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..410
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 416 AA; 45900 MW; 5CB7E60A11D717B6 CRC64;
MRNLSIIISN FIKTTFRSLK YRDFRLFWFG QCISLTGTWL QRTAQVWLVY TLTESPLMVG
IIGVCQFMPL MLFSLFAGVI VDRFPKKKIL LFTQIVFMLQ AGLMTVLTFT GAIRVEHVLV
LSVIYGLNQT LDTPARQSFF IHLVGRENVT NAISLNSTIF NLARIVGPAL SGFLMVKFSM
VFCFFMNTVS FIPVIAGIAM IKSGGEVPHH VTGHVLSQVA GGLRYVFKND TLILNMLAMA
VFCTFAMNND VIIPVFAREV LGRGAEGYTG LLSASGIGAF IGAIVLAYIS RHGMNKKMLL
FAGTLSATIQ VLMYFSRQYL LSALLLAAIG FINIAFLNTA NSIFQLNSSD EYRGRVMSVY
AFLNQGSTPI GNFFAGTAME HLGGEYGYIS CGGVTLLALA IIFVLRRKTV KSWLAE
//
