ID   A0A078M5D6_9STAP        Unreviewed;       362 AA.
AC   A0A078M5D6;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Cystathionine gamma-synthase/O-acetylhomoserine (Thiol)-lyase {ECO:0000313|EMBL:CEA01530.1};
GN   Name=metI_1 {ECO:0000313|EMBL:CEA01530.1};
GN   ORFNames=BN1048_01402 {ECO:0000313|EMBL:CEA01530.1};
OS   Jeotgalicoccus saudimassiliensis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC   Jeotgalicoccus.
OX   NCBI_TaxID=1461582 {ECO:0000313|EMBL:CEA01530.1, ECO:0000313|Proteomes:UP000044136};
RN   [1] {ECO:0000313|EMBL:CEA01530.1, ECO:0000313|Proteomes:UP000044136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=13MG44_air {ECO:0000313|EMBL:CEA01530.1,
RC   ECO:0000313|Proteomes:UP000044136};
RA   Urmite Genomes Urmite Genomes;
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|RuleBase:RU362118}.
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DR   EMBL; CCSE01000001; CEA01530.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A078M5D6; -.
DR   STRING; 1461582.BN1048_01402; -.
DR   eggNOG; COG0626; Bacteria.
DR   HOGENOM; CLU_018986_2_1_9; -.
DR   Proteomes; UP000044136; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   CDD; cd00614; CGS_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 2.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR11808:SF91; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR   PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:CEA01530.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR001434-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000044136}.
FT   MOD_RES         192
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ   SEQUENCE   362 AA;  40452 MW;  D69F246D5A45D753 CRC64;
     MDTKLSQISL KPDHTGATTS PIYLSTAFKH DGVGQSTGFD YTRTKNPTRS HFEEAFAELE
     GGTHSFATSS GMAAVQLCCN LLNSGDEVIV SFDLYGGTYR IFDFYEKKYN IRFHYADFNN
     HEELTSLITR KTRAFFIEPI TNPSMETTDL PPLYKIAQEN NILTIIDNTF LTPYLSRPLT
     EGADIVLHSA TKYIGGHNDV LAGVVTVKDE TLAEQLGLYH NMIGATLSPF DGFLLLRGLK
     TLHVRMDRQI DNAKKVAAHF KNHEAVDKVL YAGTTGMLSL RFKKTHSVNT FLEKIELCTF
     AESLGGTETF ITFPFTQTHA EMPDEERIKR GIDDSLIRLS IGIENADDII QDIEQAISQS
     VK
//