ID   A0A080M8V7_9PROT        Unreviewed;      1176 AA.
AC   A0A080M8V7;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Indolepyruvate ferredoxin oxidoreductase {ECO:0000313|EMBL:KFB77717.1};
GN   ORFNames=AW06_001091 {ECO:0000313|EMBL:KFB77717.1};
OS   Candidatus Accumulibacter cognatus.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX   NCBI_TaxID=2954383 {ECO:0000313|EMBL:KFB77717.1, ECO:0000313|Proteomes:UP000021315};
RN   [1] {ECO:0000313|EMBL:KFB77717.1, ECO:0000313|Proteomes:UP000021315}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK-02 {ECO:0000313|Proteomes:UP000021315};
RA   Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT   "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT   clades.";
RL   Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFB77717.1}.
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DR   EMBL; JDST02000018; KFB77717.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A080M8V7; -.
DR   STRING; 1453999.AW06_001091; -.
DR   Proteomes; UP000021315; Unassembled WGS sequence.
DR   GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR   CDD; cd02008; TPP_IOR_alpha; 1.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR046667; DUF6537.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR   PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR   Pfam; PF20169; DUF6537; 1.
DR   Pfam; PF01558; POR; 1.
DR   SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Pyruvate {ECO:0000313|EMBL:KFB77717.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000021315}.
FT   DOMAIN          653..683
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   1176 AA;  128810 MW;  82A0FBF6B4EBF485 CRC64;
     MGDLSTTLDS RYTANSGRVF LSGTQALVRL PMLQRMRDEA AGLNTAGFVS GYRGSPLGGL
     DQALWKARPH LDARRIVFQP GVNEDLAATA VWGTQQLNLF PGAKYEGVFA MWYGKGPGVD
     RCGDVFRHAN AAGSAKHGGV LVIAGDDHAA KSSTLPHQTE HVFKAVMMPV LYPANVQEYL
     DYGLHGWAMS RYSGCWVVMK ALADTVETSA SVSIDPLSIQ IRLPDDFEMP KNDPHALNIR
     WPDPPLQQEA RLLNHKLYAA LAYCRANQLN RVVIDSADPA SPARLGIITA GKAYLDVRQA
     LDELGIDDEL AAQIGIRLYK VGMVWPLEAD GVRRFAEGLE EILVVEEKRQ LLEYQLKEEL
     YNWREDVRPR VVGKFDEKGE WALLPTGSGH LTHGDWLLPA AGELSVAQVA RALAARIGRF
     FTSSAIEARL ALLEAKQRSL AQGLLPATGM AAIQRTPYFC SGCPHNTSTR VPEGSRAVAG
     IGCHYMVTWM DRNTATFTHM GGEGVTWVGQ APFSSEKHIF ANLGDGTYFH SGLLAIRQAV
     AAGVAITYKI LYNDAVAMTG GQPVDGPLSV AQLSRQLAAE GIQRIVIVTD EPEKYRKVPD
     LAPNTPIHHR DQLDAVQREL RNHPGVSVLI YDQTCATEKR RRRKRGKLAD PARRVFINTA
     VCEGCGDCGV QSNCLAVIPV ETEFGRKRAI DQSACNKDFS CIQGFCPSFV SVEGGRLRRG
     RAIAAAEAVL PEPLLPDTRH PYNILITGVG GTGVVTLGAL LGMAAHLDGK GVSVLDMTGL
     AQKFGTVFSH LRIADRPEDI HAARIATGEA HAVIGGDLVV SAGAEALSKV LAGKTRAVVN
     VAETPTAEFT RNPDWQFPQE HLQEQISEAC GEGNALFLDT AAMSRRLMGD ALYGNLLLLG
     VAWQRGLVPL SLAAIDQAIE LNATAVEQNR QAFLWGRRAA HDPEALQNLL NPTGMPAPQR
     LSRNLDELIR QRVETLTAYQ NARYAERYRA LVERVSAAES PLQSTALSEA VARSYFRLLA
     VKDEYEVARL HSDPAFLQQL SEEFEGDYRL RFHLAPPLLA RLDPATGRVR KSSYGPWMMS
     IFKGLSRLRF LRGTIFDPFG KTQERRMERQ LLADYEADVE LMLTRLEEKT QAIAIELAKV
     PEQIRGYGHV KAASVLPARA RRAMLRAQLE ALANAS
//