ID A0A080MCS1_9PROT Unreviewed; 483 AA.
AC A0A080MCS1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN Name=adrA_4 {ECO:0000313|EMBL:KFB74979.1};
GN ORFNames=AW06_004035 {ECO:0000313|EMBL:KFB74979.1};
OS Candidatus Accumulibacter cognatus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX NCBI_TaxID=2954383 {ECO:0000313|EMBL:KFB74979.1, ECO:0000313|Proteomes:UP000021315};
RN [1] {ECO:0000313|EMBL:KFB74979.1, ECO:0000313|Proteomes:UP000021315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-02 {ECO:0000313|Proteomes:UP000021315};
RA Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT clades.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the hemerythrin family.
CC {ECO:0000256|ARBA:ARBA00010587}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFB74979.1}.
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DR EMBL; JDST02000111; KFB74979.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A080MCS1; -.
DR STRING; 1453999.AW06_004035; -.
DR Proteomes; UP000021315; Unassembled WGS sequence.
DR GO; GO:0052621; F:diguanylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd12107; Hemerythrin; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.20.120.50; Hemerythrin-like; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR012312; Hemerythrin-like.
DR InterPro; IPR035938; Hemerythrin-like_sf.
DR InterPro; IPR012827; Hemerythrin_metal-bd.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR02481; hemeryth_dom; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF01814; Hemerythrin; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF47188; Hemerythrin-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000313|EMBL:KFB74979.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000021315};
KW Transferase {ECO:0000313|EMBL:KFB74979.1}.
FT DOMAIN 195..324
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT COILED 137..167
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 483 AA; 53849 MW; 3AE6CF43558F49CD CRC64;
MNDDELIRTL AEDRVIPMAG LLSLLMPASA GVGFSLKGLD GRYRLVNREM ERLLGQGPAC
LVGRSESDVL PTHLLAQLAH CDQRILDGAS ASYEEVEMPV DGRISRCRWI NLSVFGTDHK
LQSIASIVQE TFPSPEISSM QQTLDRLRQA NQELQRTVGE LEQVASTDKL TGAWNRRRLE
ECVRSEMDRL NRYEQPLSLL LVDIDHFKAI NDQHGHGVGD QILQTMTSML QSRLRGTDAL
ARWGGEEFVV ICPNTGRSTA ALLAERVRVQ IASADFPLIG QLTVSIGAAE CNPGDTWEEW
FQRADEALYR AKTGGRNQVQ LAPAAVRPPD TQGYVVANFV QLVWQSAYEC GNELVDRGHR
QLFADANELL AAILGQYEAR RLDLIVETLT TDVVRHFADE ESVIHAAGYP GAAEHAVLHR
ELVAQARRLL DDYRAGKQGV GDLFQFLAYD VVTRHMLGED RKFFPYLRTQ VAAPVRNREA
PSP
//
