ID A0A080MF65_9PROT Unreviewed; 626 AA.
AC A0A080MF65;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Methyl-accepting chemotaxis protein 4 {ECO:0000313|EMBL:KFB75864.1};
GN Name=mcp4_5 {ECO:0000313|EMBL:KFB75864.1};
GN ORFNames=AW06_003097 {ECO:0000313|EMBL:KFB75864.1};
OS Candidatus Accumulibacter cognatus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX NCBI_TaxID=2954383 {ECO:0000313|EMBL:KFB75864.1, ECO:0000313|Proteomes:UP000021315};
RN [1] {ECO:0000313|EMBL:KFB75864.1, ECO:0000313|Proteomes:UP000021315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-02 {ECO:0000313|Proteomes:UP000021315};
RA Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT clades.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFB75864.1}.
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DR EMBL; JDST02000071; KFB75864.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A080MF65; -.
DR STRING; 1453999.AW06_003097; -.
DR Proteomes; UP000021315; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR Gene3D; 1.20.120.1530; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR033480; sCache_2.
DR PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF18947; HAMP_2; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF17200; sCache_2; 1.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00304; HAMP; 2.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000021315};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 212..264
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 303..355
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 360..575
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 595..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 561..591
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 606..626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 626 AA; 66706 MW; 8AA4F4D669B0BDF5 CRC64;
MNWLRSMKVS TRNLLWGGLT AIGLLLFCTV SLVSIHDNML EDRKQRIKSL VEAGIGVLKH
YHQLSATGKL SDKDARNTAL DALRHMRYEG GNYLFVFDPE GLFYLMPASP DFEGTNKIDL
KDANGKYLIR ELISVAKAGG GYVAYDFPKP GTQAASPKIG HAELFAPWNL VIGTGIYIDD
VDVVFRRVLI QLVSISLALL ALLTAMGWAI SRSISGPLNS VVEVSGRMAA GDFDFKLDTT
GRDEAGAVFR AVMMVKEAVH AMISDAGALS TAAAKGRLET RVDAARHQGE YRNIIEGLNR
TMDAVVDPIN DVKRVMAAVE RGDLGQSIDA EYQGDFGALQ ASVNNTLAKL SATIAQVNTS
AGELSNASTQ VSATSQLLSQ ATSEQASSLE QTTAAMEQMS ASIAQNTDNA KTTDSIARQS
AADALAGGEA VRSTVAAMKS IAGKISIIDD IAYRTDLLAL NAAIEAARAG EHGKGFAVVA
AEVRKLAERS QIAAQEIGEL ASSSVETAER AGSLFETMLP SIRKTADLVG EITAASEEQT
TGADQISQAM AQLNTVTQQN AATAEELSAT AEEMNAQAEN LNELMAQFTL ASNDVVMPAR
PGRTARPGKA KRESAANHPL KDYERF
//
