ID A0A080WPP1_TRIRC Unreviewed; 346 AA.
AC A0A080WPP1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=AMP-binding enzyme {ECO:0008006|Google:ProtNLM};
GN ORFNames=TERG_07849 {ECO:0000313|EMBL:KFL62852.1};
OS Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=559305 {ECO:0000313|EMBL:KFL62852.1, ECO:0000313|Proteomes:UP000008864};
RN [1] {ECO:0000313|EMBL:KFL62852.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 118892 {ECO:0000313|EMBL:KFL62852.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Henn M., Martinez D., Young S.K., Zeng Q., Gargeya S., Haas B.,
RA Alvarado L., Berlin A., Chapman S., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Howarth C.,
RA Larson L., Mehta T., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., White T.C.,
RA Abdel-Rahman S., Graser Y., Gurr S.J., Kohler G., Martinez-Rossi N.,
RA Oliver B.C., Rossi A., Shelest E., Summerbell R., Lander E., Nusbaum C.,
RA Birren B.;
RT "Annotation of Trichophyton rubrum strain CBS 118892.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000008864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4607 / CBS 118892 {ECO:0000313|Proteomes:UP000008864};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
RN [3] {ECO:0000313|EMBL:KFL62852.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 118892 {ECO:0000313|EMBL:KFL62852.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., White T.C., Graser Y., Martinez-Rossi N., Heitman J.,
RA Young S.K., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., Martinez D., Murphy C., Pearson M.D.,
RA Persinoti G., Poon T., Priest M., Roberts A.D., Saif S., Shea T.D.,
RA Sykes S.N., Wortman J., Nusbaum C., Birren B.;
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG700658; KFL62851.1; -; Genomic_DNA.
DR EMBL; GG700658; KFL62852.1; -; Genomic_DNA.
DR eggNOG; KOG1177; Eukaryota.
DR HOGENOM; CLU_000022_59_7_1; -.
DR OrthoDB; 2596785at2759; -.
DR Proteomes; UP000008864; Unassembled WGS sequence.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF29; ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G08470)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008864}.
FT DOMAIN 7..230
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 285..343
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 346 AA; 37310 MW; FCB2D20F6D993C7A CRC64;
MKALPDQGLS PTDVVNIQFT SGTTSMPKAA CLSHRSILNN GVQIGDRMLL TPKDIVCCPP
PLFHCFGCIL GYMATATHGS AIVFPTESFN AVATLKAVQE EKCTALYGVP TMFIEELDLL
ADGVVPYEGF QYLRTGIAAG SSVPSELMKK LHKTLNLTEL TICYGMTETS PVSTMTATDD
PIEKRLNTVG KLLPHVEAKV VNPLDYDQIL PLGERGELAV SGYHVMKEYW GAPEKTAAVM
VPDSEGKIWM HTGDEASMSA DGYITITGRI KDLIIRGGEN IHPLEVENCL LAHPSVSNVS
VLGVPDERYG EAVAAFVVTH AEGEGKVTSA EIKSWVRGKL SHHLGK
//
