ID   A0A081BH57_9LACO        Unreviewed;       263 AA.
AC   A0A081BH57;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=Pur operon repressor {ECO:0000256|ARBA:ARBA00018449};
GN   Name=purR {ECO:0000313|EMBL:GAK47375.1};
GN   ORFNames=LOSG293_050450 {ECO:0000313|EMBL:GAK47375.1};
OS   Secundilactobacillus oryzae JCM 18671.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Secundilactobacillus.
OX   NCBI_TaxID=1291743 {ECO:0000313|EMBL:GAK47375.1, ECO:0000313|Proteomes:UP000028700};
RN   [1] {ECO:0000313|EMBL:GAK47375.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SG293 {ECO:0000313|EMBL:GAK47375.1};
RA   Tanizawa Y., Fujisawa T., Mochizuki T., Kaminuma E., Nakamura Y., Tohno M.;
RT   "Draft Genome Sequence of Lactobacillus oryzae Strain SG293T.";
RL   Genome Announc. 2:e00861-14(2014).
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC       family. {ECO:0000256|ARBA:ARBA00008391}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAK47375.1}.
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DR   EMBL; BBJM01000005; GAK47375.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A081BH57; -.
DR   STRING; 1291743.LOSG293_050450; -.
DR   eggNOG; COG0503; Bacteria.
DR   Proteomes; UP000028700; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0045982; P:negative regulation of purine nucleobase metabolic process; IEA:InterPro.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   InterPro; IPR015265; PuR_N.
DR   InterPro; IPR010078; PurR_Bsub.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR01743; purR_Bsub; 1.
DR   PANTHER; PTHR43864; HYPOXANTHINE/GUANINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR43864:SF2; PUR OPERON REPRESSOR; 1.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   Pfam; PF09182; PuR_N; 1.
DR   SUPFAM; SSF53271; PRTase-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Glycosyltransferase {ECO:0000313|EMBL:GAK47375.1};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transferase {ECO:0000313|EMBL:GAK47375.1}.
FT   DOMAIN          1..62
FT                   /note="Bacterial purine repressor N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09182"
FT   DOMAIN          97..242
FT                   /note="Phosphoribosyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00156"
SQ   SEQUENCE   263 AA;  28651 MW;  FA0D16FD8427A807 CRC64;
     MTRYLLERPH TLVSLTFFAT RYGSAKSSIS EDLTILKRTF QERGTGILET VPGAAGGARF
     IPGISEEEAI LFVRKMETAL TEENRFLPGG YVYMSDLLGQ PDVLRQVGRI IATEYQEGAV
     DAVMTVATKG VPIAQSVASF LNVPFVIVRH DSQITEGSTV SVNYVSGSSN RIEKMALSKR
     SLKSGSRVLV VDDYMKAGGT VRGMQSLVKE FDSTVVGISV FAEGADTEDK VIEDYTSLLT
     VGVENEQVKV APGNYLEKIF SKK
//