ID A0A081CGY5_PSEA2 Unreviewed; 662 AA.
AC A0A081CGY5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Related to Tumor susceptibility gene 101 protein {ECO:0000313|EMBL:SPO45564.1};
GN ORFNames=PAN0_010d4153 {ECO:0000313|EMBL:GAK65931.1}, PSANT_03250
GN {ECO:0000313|EMBL:SPO45564.1};
OS Pseudozyma antarctica (Yeast) (Candida antarctica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces.
OX NCBI_TaxID=84753 {ECO:0000313|EMBL:GAK65931.1, ECO:0000313|Proteomes:UP000053758};
RN [1] {ECO:0000313|Proteomes:UP000053758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10317 {ECO:0000313|Proteomes:UP000053758};
RA Saika A., Koike H., Hori T., Fukuoka T., Sato S., Habe H., Kitamoto D.,
RA Morita T.;
RT "Draft Genome Sequence of the Yeast Pseudozyma antarctica Type Strain
RT JCM10317, a Producer of the Glycolipid Biosurfactants, Mannosylerythritol
RT Lipids.";
RL Genome Announc. 2:e00878-e00814(2014).
RN [2] {ECO:0000313|EMBL:GAK65931.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 10317 {ECO:0000313|EMBL:GAK65931.1};
RA Morita T., Saika A., Koike H.;
RT "Draft genome sequence of the yeast Pseudozyma antarctica JCM 10317 known
RT as a producer of lipase B which used in a wide range of industrial
RT applications.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:SPO45564.1, ECO:0000313|Proteomes:UP000325008}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34888 {ECO:0000313|Proteomes:UP000325008}, and ATCC34888
RC {ECO:0000313|EMBL:SPO45564.1};
RA Guldener U.;
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UEV
CC subfamily. {ECO:0000256|ARBA:ARBA00009594}.
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DR EMBL; DF830077; GAK65931.1; -; Genomic_DNA.
DR EMBL; OOIQ01000006; SPO45564.1; -; Genomic_DNA.
DR RefSeq; XP_014656093.1; XM_014800607.1.
DR AlphaFoldDB; A0A081CGY5; -.
DR GeneID; 26304980; -.
DR HOGENOM; CLU_017548_2_0_1; -.
DR OrthoDB; 37962at2759; -.
DR Proteomes; UP000053758; Unassembled WGS sequence.
DR Proteomes; UP000325008; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0072666; P:establishment of protein localization to vacuole; IEA:UniProt.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:UniProt.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR Gene3D; 6.10.140.820; -; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR017916; SB_dom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR008883; UEV_N.
DR PANTHER; PTHR23306:SF3; TUMOR SUPPRESSOR PROTEIN 101; 1.
DR PANTHER; PTHR23306; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED; 1.
DR Pfam; PF05743; UEV; 1.
DR Pfam; PF09454; Vps23_core; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS51312; SB; 1.
DR PROSITE; PS51322; UEV; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000053758};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 4..149
FT /note="UEV"
FT /evidence="ECO:0000259|PROSITE:PS51322"
FT DOMAIN 597..662
FT /note="SB"
FT /evidence="ECO:0000259|PROSITE:PS51312"
FT REGION 144..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..218
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..421
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 662 AA; 70848 MW; DD7BD7F5D6C0883B CRC64;
MDHAVVQRWL RSVLGPYNDR DRVYADVDRA LIAVSSLSPK TEVFTFNDGR TQLLLTLEGT
VPVEFRTTTY NIPVAYWIPR DYPREPPMAF VAPTPDMAIR KGPNVDPSGQ IGGNYIARWR
SKPEACNLLD LIHDCQHMFG REPPVYAKPK PTPVYATAAS SQQRSQPSTP QQGSSANPLA
QPPGPSLPAS PRSPQVVGSP SLEARQRPPP PPPGPGSAHH DHPQGSSTPQ RPPKPSSSMG
FDRSGFHSPR SSSSHFDPHQ SPAPLPALQI QSPHTFGHPP GAGSDVNRRA SGGAYGPGAH
QAPFGAPSPQ AHFAPADRTQ TRIESSHSPV SPSHRPAYAD GRPYAYGHQS TPQQHPPTRA
QTYPYPTQEP HPSHTQYGNE AAQAGGRQPA YSGAPGAQSY AQPGLPPANG GGPPPVPGPH
PYASGSVSQA PNPAAVAVAD RNGVPARPTA APRPKSVNLL DDEDSALGIS DTRGQANGFA
SAGGPTSAGS SAPPPPRPIN PELLALHERV YSKIDQRLVT LSSTLQASNQ RLEVLSSDLD
RGLPAIEDEM SRLKAVRDVC KITGDRLQGS VDEITESVRS IHARDDPDPD SMVLATSIVG
NQLVDLVAED NAIEDTLYHL GRALNAERID LDRFLKQTRM LAREQFMKRA LAHKISEGMG
WS
//
