ID A0A081CH49_PSEA2 Unreviewed; 610 AA.
AC A0A081CH49;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE SubName: Full=Nucleoside transporter {ECO:0000313|EMBL:GAK65995.1};
DE SubName: Full=Probable purine permease {ECO:0000313|EMBL:SPO46769.1};
GN ORFNames=PAN0_011c4217 {ECO:0000313|EMBL:GAK65995.1}, PSANT_04455
GN {ECO:0000313|EMBL:SPO46769.1};
OS Pseudozyma antarctica (Yeast) (Candida antarctica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces.
OX NCBI_TaxID=84753 {ECO:0000313|EMBL:GAK65995.1, ECO:0000313|Proteomes:UP000053758};
RN [1] {ECO:0000313|Proteomes:UP000053758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10317 {ECO:0000313|Proteomes:UP000053758};
RA Saika A., Koike H., Hori T., Fukuoka T., Sato S., Habe H., Kitamoto D.,
RA Morita T.;
RT "Draft Genome Sequence of the Yeast Pseudozyma antarctica Type Strain
RT JCM10317, a Producer of the Glycolipid Biosurfactants, Mannosylerythritol
RT Lipids.";
RL Genome Announc. 2:e00878-e00814(2014).
RN [2] {ECO:0000313|EMBL:GAK65995.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 10317 {ECO:0000313|EMBL:GAK65995.1};
RA Morita T., Saika A., Koike H.;
RT "Draft genome sequence of the yeast Pseudozyma antarctica JCM 10317 known
RT as a producer of lipase B which used in a wide range of industrial
RT applications.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:SPO46769.1, ECO:0000313|Proteomes:UP000325008}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34888 {ECO:0000313|Proteomes:UP000325008}, and ATCC34888
RC {ECO:0000313|EMBL:SPO46769.1};
RA Guldener U.;
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; DF830078; GAK65995.1; -; Genomic_DNA.
DR EMBL; OOIQ01000011; SPO46769.1; -; Genomic_DNA.
DR RefSeq; XP_014655673.1; XM_014800187.1.
DR AlphaFoldDB; A0A081CH49; -.
DR GeneID; 26305015; -.
DR HOGENOM; CLU_017959_7_0_1; -.
DR OrthoDB; 911690at2759; -.
DR Proteomes; UP000053758; Unassembled WGS sequence.
DR Proteomes; UP000325008; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053758};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 521..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 562..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 64050 MW; B4B7FE7A9D45C221 CRC64;
MEAKPAVTVD EGSLATLPDP PARSFVGKVK RGVRALGTRD AWFGDHNYVA LFTPTVPFLC
KADTTSLPFY SVNARLPIFL ACILGVQHFL AMAGGVVTPP LLIGGSSGAN LGQEDTQFLI
ASTLIWCAFG TALQVSRNRI FKTKYYIGTG IISVTGASFA TISIALSFFA QSYANGYCPT
GANGVKLPCP QAVGAFLGTC CLCGLISIAM AFIPPKAIRK LFPPLIVGMM LTLIGASLVK
SGITNWAGGS APCATNHAIK CKIGSRMQFW GSAPLIGLGF TSFFTIILCE IFGSPFLKSA
SVFVGLVVGM IVAAATGYFN TTLMHNAPAG SFLWTKTFPL SIKPELILPL LAAYVVIVAE
TVGNVTASCD ASRLPMDGTE FESRIQGGML ADSISATLAG LAMVPPLTTF SQNSGVISLT
RNASRTAGYI CAAMLFLAGI VGKFSSLFVA MPSSVLGGFT TFLFGSVAVA GIRIMAYAKW
DRRARFIATS GMSLGLASLT VPSWFSYFFT YSGSNAGLKG LIQAIVLIVE EPYLISSLLA
ILLNTILPAE PEDEQASQLL EDDAASNSGS DVKIDSDQPA AEVPDLESGA PATEAAKKAW
NQPGTFFGRK
//
