ID A0A081G1R0_9GAMM Unreviewed; 511 AA.
AC A0A081G1R0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Acetyl-CoA hydrolase {ECO:0000313|EMBL:KEA64715.1};
DE EC=3.1.2.1 {ECO:0000313|EMBL:KEA64715.1};
GN ORFNames=ADIMK_1168 {ECO:0000313|EMBL:KEA64715.1};
OS Marinobacterium lacunae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinobacterium.
OX NCBI_TaxID=1232683 {ECO:0000313|EMBL:KEA64715.1, ECO:0000313|Proteomes:UP000028252};
RN [1] {ECO:0000313|EMBL:KEA64715.1, ECO:0000313|Proteomes:UP000028252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK27 {ECO:0000313|EMBL:KEA64715.1,
RC ECO:0000313|Proteomes:UP000028252};
RA Singh A., Pinnaka A.K.;
RT "Marinobacterium kochiensis sp. nov., isolated from sediment sample
RT collected from Kochi backwaters in Kerala, India.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEA64715.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JMQN01000015; KEA64715.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A081G1R0; -.
DR STRING; 1232683.ADIMK_1168; -.
DR PATRIC; fig|1232683.4.peg.1158; -.
DR eggNOG; COG0427; Bacteria.
DR Proteomes; UP000028252; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:KEA64715.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000028252}.
FT DOMAIN 19..180
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 332..478
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 303
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 373
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 393
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 397
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 417
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 511 AA; 56139 MW; B146C98C86B06A27 CRC64;
MKSEEKIMSS PSRILCERLR QRIVSADEAA AMIPRGANVG MSGFTGAGYP KAVPGALANR
IRTLNTEGGQ PFRINIWTGA STAPELDGVL AEVDGIEMRL PFQSDPICRD RINSGKMEYV
DYHLSEVSQY AWSGFLGKMD IALIEVAGIR EDGSLIPSSS IGNNKTWIEQ ADKIILEVNS
RQNAKLEGMH DIYYGTALPP NRKPIMLTDP ADRIGEHYLS CPIDKVIAVV ETDAPDRNSP
FKSPDDVSKR IAGHILDFFQ REIEIGRLPK ELLPIQSGVG NIPNAVLEGL DAGPFKNLTA
FTEVIQDGML KMLKSGTLKV ASATAFSLSP DGIKEFDTNI DLYRDKIILR QQDISNHPEL
ARRLGIIAMN GLIEADIYGN VNSTHIMGTR MMNGIGGSGD FARNGYLSIF VSPSTAKNGA
ISSIVPMVSH VDHTEHDVKI IVTEQGLADL RGLSPRQRAH AIISNCAHPD FKPALMDYYE
RALHSGRGQH TPHLLEEALS WHCRYEQTGR M
//
