ID   A0A081KES2_9GAMM        Unreviewed;       590 AA.
AC   A0A081KES2;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=3-oxosteroid 1-dehydrogenase {ECO:0000313|EMBL:KEI72648.1};
GN   ORFNames=GV64_19635 {ECO:0000313|EMBL:KEI72648.1};
OS   Endozoicomonas elysicola.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Endozoicomonadaceae; Endozoicomonas.
OX   NCBI_TaxID=305900 {ECO:0000313|EMBL:KEI72648.1, ECO:0000313|Proteomes:UP000027997};
RN   [1] {ECO:0000313|EMBL:KEI72648.1, ECO:0000313|Proteomes:UP000027997}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22380 {ECO:0000313|EMBL:KEI72648.1,
RC   ECO:0000313|Proteomes:UP000027997};
RA   Neave M.J., Apprill A., Voolstra C.R.;
RT   "Whole Genome Sequences of Three Symbiotic Endozoicomonas Bacteria.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KEI72648.1}.
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DR   EMBL; JOJP01000001; KEI72648.1; -; Genomic_DNA.
DR   RefSeq; WP_020581300.1; NZ_JOJP01000001.1.
DR   AlphaFoldDB; A0A081KES2; -.
DR   STRING; 305900.GV64_19635; -.
DR   eggNOG; COG1053; Bacteria.
DR   Proteomes; UP000027997; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027997}.
FT   DOMAIN          19..551
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
SQ   SEQUENCE   590 AA;  64525 MW;  CEFC7404E811800C CRC64;
     MDSSNNKKGG SKPWDTIVDV VVVGSGAGAL TASLRAHDLG LKTLVVEKTE QYGGTSAISG
     GGIWIPNSFQ MQAMGVKDSD EVAVDYIKRV IGEEPGDGRI EAYVANAKKM LRYLEENTRV
     RYEAQSAYAD YYPELPGGMP GYRSMDPMPF HASKLGSEFE NLRPTTPATL MLGRMAMTMK
     EARVLLCRGK GFLLTNMRIM WRYYRDIFWR LKSKRDRFLT LGNALIAALR ASMLDRDIPL
     WLNSPMESLV EENGQVIGVV VNRDGKPLRV KARKGVIIGA GGFESNQAMR DQYHPQPSQS
     LWSAAPEGIN TGDGIQAGQN LGAATALMEH SWWAPTSHVE AETRSRAMFV ERALPNCILV
     NKDGKRFMNE AAPYNDFGDG MYGTESVPCW FVFDAQYRHK YPCGALLPGY AVPDKAVPKR
     YKNFFQKAES LEALAEKIGV DASGLQETVV NYNQYSAEGK DPEFGKGDSL FDRYYGDPNT
     TPNPCLGPLE KGPFYAVKVN IGDIGTKGGL VTDVDGQVLK EDGSPISGLY AIGNTSASVM
     KQTYPGAGST IGPAMTFGYL SANHVAQRQV DARTVKAAEN TQENKNAVEA
//