ID A0A081NIX2_9GAMM Unreviewed; 440 AA.
AC A0A081NIX2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Sodium:proton antiporter {ECO:0000313|EMBL:KEQ18395.1};
GN ORFNames=GZ78_12900 {ECO:0000313|EMBL:KEQ18395.1};
OS Endozoicomonas numazuensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Endozoicomonadaceae; Endozoicomonas.
OX NCBI_TaxID=1137799 {ECO:0000313|EMBL:KEQ18395.1, ECO:0000313|Proteomes:UP000028073};
RN [1] {ECO:0000313|EMBL:KEQ18395.1, ECO:0000313|Proteomes:UP000028073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25634 {ECO:0000313|EMBL:KEQ18395.1,
RC ECO:0000313|Proteomes:UP000028073};
RA Neave M.J., Apprill A., Voolstra C.R.;
RT "Whole Genome Sequences of Three Symbiotic Endozoicomonas Bacteria.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEQ18395.1}.
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DR EMBL; JOKH01000002; KEQ18395.1; -; Genomic_DNA.
DR RefSeq; WP_034835679.1; NZ_JOKH01000002.1.
DR AlphaFoldDB; A0A081NIX2; -.
DR STRING; 1137799.GZ78_12900; -.
DR eggNOG; COG2056; Bacteria.
DR OrthoDB; 9772446at2; -.
DR Proteomes; UP000028073; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR InterPro; IPR032813; Na_H_antiport_N.
DR PANTHER; PTHR37821; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR PANTHER; PTHR37821:SF1; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR Pfam; PF13726; Na_H_antiport_2; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028073};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..87
FT /note="Putative Na+/H+ antiporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13726"
FT DOMAIN 151..434
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 440 AA; 46688 MW; F4A6AA06AC6850BD CRC64;
MNAVILAVVV MLALSLLRVN VVLALFVGAM AGGVIGGLDI IQTLEAFSRG LGGGVGIAIS
YAMLGAFAVA IARSGIPEWM AGKIIRKVKS SNSSHNNLKL KYSLFLAIVL MAFSSQNLVP
IHIAFIPILI PPLLSVFSAM EIDRRQVACL LTFGLTATYM LLPIGFGSMY LHQILGGNLL
ANGLDIEMSQ MPLAMAIPVF GMFLGLLIAV FFSYRKPRKY RVEETLLIHE QDIQLSKSAI
ITSLIAIVLV LVSQLMTGSM VLGAALGFIT MVVGRVVCWR EADEVFNEGL RMMAVFGFIM
ISAAGFAEVL RSTGDIPELV AQIQTIVGGS QGLAAILMLL VGLLITMGIG SSFSTVPIIA
TLYVPLGMEL GFTSLAIACL VGASGAVGDA GSPVSESTIG PTAGLNVDDQ HDHIWDSVIP
TFLHYNIPMI IFGWIAAMIL
//
