ID A0A083ZWC7_9GAMM Unreviewed; 758 AA.
AC A0A083ZWC7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=ComEC family competence protein {ECO:0000313|EMBL:KEY57356.1};
GN ORFNames=SRDD_37260 {ECO:0000313|EMBL:KEY57356.1};
OS Serratia sp. DD3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=1410619 {ECO:0000313|EMBL:KEY57356.1, ECO:0000313|Proteomes:UP000017810};
RN [1] {ECO:0000313|EMBL:KEY57356.1, ECO:0000313|Proteomes:UP000017810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DD3 {ECO:0000313|EMBL:KEY57356.1,
RC ECO:0000313|Proteomes:UP000017810};
RX PubMed=25212623;
RA Poehlein A., Freese H.M., Daniel R., Simeonova D.D.;
RT "Draft Genome Sequence of Serratia sp. Strain DD3, Isolated from the Guts
RT of Daphnia magna.";
RL Genome Announc. 2:e00903-14(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEY57356.1}.
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DR EMBL; AYKS02000092; KEY57356.1; -; Genomic_DNA.
DR RefSeq; WP_023489343.1; NZ_AYKS02000092.1.
DR AlphaFoldDB; A0A083ZWC7; -.
DR STRING; 1410619.SRDD_37260; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR Proteomes; UP000017810; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017810};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 513..693
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 758 AA; 86557 MW; 2F0089DC21330D47 CRC64;
MDIRVSIDTA AMALVTGMLP LLFLPYLPTW SQLSGVAFVA LLLWRQKQQY WCQVLCYLLL
GFILATGSAS VLMRQVTTLS VGGDQDVMAT VRSIKLEGVE IPQVQFRIEQ VNGRWLIPAL
TFIAQSPSEN ICAGQQWALK VRFRPVHSSL NEGGFDGQRW AMANRQPLRG YLRSATVVNE
NCHWRQQIIT TMDNQWRELA QRPVLLALAF GERMLMDGNS RAQLMKTGIA HLMAISGLHI
SLAAAFAWAG ARGVQFFLPA RLIGYRLPLL TGWVMALSYV WLAGGQPPAM RAFIALSLWL
WLRFKGVSCS SWQVWLWCIC LLLLFDPLAI LSDSFWLSVL AVAALIFWFE WAPLSVRFTS
FWGWAPLRWL HIQLGMTLLL MPLQFGLFHG VSWTSLPANL WAVPIISLLS VPLILLAMIL
FFIPWLSFWC WKLADLTISW ALWPLPWLEQ GWVQVGALLL QFSTLGWLVV IGWRFEWWRC
FPAGCITVVL VCLLWRERSA DYHWRVDMLD VGHGLAVVIE REGKAVIYDS GNRWTTSSAA
ERIILPFLHW RQISLEHIII SHSHLDHIGG LPVLEQAFPQ AAVHTPLIHE RHLPCLQGQQ
WTWRGLNFQV LWPPQRVEQA GNDDSCVVRV DDGKFSLLLT GDIERRAEQG LLRQRAKLPA
TLLQVPHHGS RTSSSPPFLR AVAPELAMAS VARYNAWRLP AVKVIKDYRQ NHIAWHDTAH
SGQLSVFFFD NSWQIKGFRE QINPRWYHQW FGVKSDNE
//
