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Database: UniProt
Entry: A0A084GKP1_BACID
LinkDB: A0A084GKP1_BACID
Original site: A0A084GKP1_BACID 
ID   A0A084GKP1_BACID        Unreviewed;       794 AA.
AC   A0A084GKP1;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   08-MAY-2019, entry version 27.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:KEZ47903.1};
GN   ORFNames=GS18_0218125 {ECO:0000313|EMBL:KEZ47903.1};
OS   Bacillus indicus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=246786 {ECO:0000313|EMBL:KEZ47903.1, ECO:0000313|Proteomes:UP000028549};
RN   [1] {ECO:0000313|EMBL:KEZ47903.1, ECO:0000313|Proteomes:UP000028549}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16189 {ECO:0000313|EMBL:KEZ47903.1,
RC   ECO:0000313|Proteomes:UP000028549};
RX   PubMed=15774653; DOI=10.1099/ijs.0.63208-0;
RA   Yoon J.H., Lee C.H., Oh T.K.;
RT   "Bacillus cibi sp. nov., isolated from jeotgal, a traditional Korean
RT   fermented seafood.";
RL   Int. J. Syst. Evol. Microbiol. 55:733-736(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a (3S)-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+)
CC         + NADH; Xref=Rhea:RHEA:22432, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57318, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:90726; EC=1.1.1.35;
CC         Evidence={ECO:0000256|SAAS:SAAS01123908};
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|SAAS:SAAS00324886}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KEZ47903.1}.
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DR   EMBL; JNVC02000015; KEZ47903.1; -; Genomic_DNA.
DR   RefSeq; WP_029566671.1; NZ_JNVC02000015.1.
DR   EnsemblBacteria; KEZ47903; KEZ47903; GS18_0218125.
DR   OrthoDB; 82358at2; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000028549; Unassembled WGS sequence.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.1040.10; -; 2.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF48179; SSF48179; 2.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000028549};
KW   Fatty acid metabolism {ECO:0000256|SAAS:SAAS00324839};
KW   Lipid metabolism {ECO:0000256|SAAS:SAAS00324863};
KW   NAD {ECO:0000256|SAAS:SAAS00830857};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00331296};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028549}.
FT   DOMAIN        7    205       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      208    306       3HCDH. {ECO:0000259|Pfam:PF00725}.
SQ   SEQUENCE   794 AA;  87226 MW;  26867484FBFEF529 CRC64;
     MNQRIRKAAV LGSGVMGSGI AAHLANIGIP VLLLDIVPRT LTDGEEKKGL TLQDAAVRNR
     ISSEAVQKLL KQKPAPLTAK GNLALIEAGN FEDDMHRLAE ADWIIEVVVE NLEVKQKVFT
     QVDQYRKQGS IVSSNTSGIS VEAMSEGRSD DFRKHFLGTH FFNPPRYLKL LEVIPTKATS
     PEILSFMKTF GEDVLGKGVV EAKDTPNFIA NRIGTYGLLV TVKELQKGGY SVGEVDSVTG
     PLIGRPKSAT FRTLDVVGLD TFAHVAKNVY DQVEGEEKDV FDIPEFMKKM LENGWLGSKS
     GQGFFKKEGK EILELNPETL EYQERKKLKA QSIEAAKQIK GSAAKMKALI YSGDRAGTLL
     WNITSPTLLY SAELLGDIAD DILAIDEAMK WGFGWQYGPF ETWDSIGLSK SVEKMEAEGK
     TVPAWIKDML ERGFTSFYKK EDGVSYYYHD GDYRRIETNE KVINLKDLKE KKGVIKKNSG
     ASLVDLGDGV ALLEFHSPNN AIGLDIIQMI NFAVDEVEKN FKGLVMGNQG KNFCVGANLA
     MILMEAQDDN YFEVDMVVRH FQQAMMKIKF SPKPVVAAPF GMSLGGGAEI CLPSASIQAS
     SETYMGLVEA GVGLIPGGGG NKELYIKLLN SVPKGVDFDL QNVANKVFET IATAKVSSSA
     AEAKENFFMN EKDSVSFNGD HLIYDAKQKV LQLSDNGYKA PVRKKVPVVG ETGYAALLLG
     AQSMLQSGYI SEHDLKIAQK LAYVIAGGKV PFGTEVDEQY LLDLEREAFL SLVKEGKSQQ
     RMQHMLVKGK PLRN
//
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