ID A0A084JFN0_9CLOT Unreviewed; 855 AA.
AC A0A084JFN0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=peptidoglycan-N-acetylglucosamine deacetylase {ECO:0000256|ARBA:ARBA00044052};
DE EC=3.5.1.104 {ECO:0000256|ARBA:ARBA00044052};
GN ORFNames=IO99_04460 {ECO:0000313|EMBL:KEZ87764.1};
OS Clostridium sulfidigenes.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=318464 {ECO:0000313|EMBL:KEZ87764.1, ECO:0000313|Proteomes:UP000028542};
RN [1] {ECO:0000313|EMBL:KEZ87764.1, ECO:0000313|Proteomes:UP000028542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=113A {ECO:0000313|EMBL:KEZ87764.1,
RC ECO:0000313|Proteomes:UP000028542};
RA Honkalas V.S., Dabir A.P., Arora P., Dhakephalkar P.K.;
RT "Draft genome of Clostridium sulfidigenes 113A isolated from sediments
RT associated with methane hydrate from Krishna Godavari basin.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=peptidoglycan-N-acetyl-D-glucosamine + H2O = peptidoglycan-D-
CC glucosamine + acetate.; EC=3.5.1.104;
CC Evidence={ECO:0000256|ARBA:ARBA00043715};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEZ87764.1}.
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DR EMBL; JPMD01000008; KEZ87764.1; -; Genomic_DNA.
DR RefSeq; WP_035130716.1; NZ_JPMD01000008.1.
DR AlphaFoldDB; A0A084JFN0; -.
DR STRING; 318464.IO99_04460; -.
DR GeneID; 84600349; -.
DR eggNOG; COG0726; Bacteria.
DR Proteomes; UP000028542; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd10917; CE4_NodB_like_6s_7s; 3.
DR Gene3D; 3.20.20.370; Glycoside hydrolase/deacetylase; 3.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR002509; NODB_dom.
DR PANTHER; PTHR10587:SF105; CHITIN DEACETYLASE 1-RELATED; 1.
DR PANTHER; PTHR10587; GLYCOSYL TRANSFERASE-RELATED; 1.
DR Pfam; PF01522; Polysacc_deac_1; 3.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 3.
DR PROSITE; PS51677; NODB; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028542};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 5..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 73..267
FT /note="NodB homology"
FT /evidence="ECO:0000259|PROSITE:PS51677"
FT DOMAIN 362..559
FT /note="NodB homology"
FT /evidence="ECO:0000259|PROSITE:PS51677"
FT DOMAIN 653..846
FT /note="NodB homology"
FT /evidence="ECO:0000259|PROSITE:PS51677"
SQ SEQUENCE 855 AA; 96276 MW; 0C491A741A5CF32C CRC64;
MKKNWIIITI IITVAVVLGA FTYKSYIKNN HTENMIKNNK NKYDASAEIK DALKLLSSKK
QAEVITNAKT SSNVLALSFE GISDANTMGK IVELLNAYGV KANFFIPGIK AGEDPTTVKN
IKKAGHVVGS ETLSDARHME KLSQKELITD FCRGNKIIET IIKEKPNLLK CKSTTYTDEV
LEAAYASGNK YVIHSDHYLS YQSFKDYGQA QNYVNKLDKG TIISIKVSGV LDDFEYEGEK
EEEKPAIDKE AGIDESTKDE REEITVVKIV EWLLKAIDEQ KITVVQVNEL VGMKSDDETS
SSENMSNKDE IYIDESYKEE KNTSQGNSEV KNSSDLVNFK ELIEKNNGNL APNISEFYTT
KKALSYTFRG LGNETALNSV LISLDKIKAK GTFFVTKDEI EKYPDRIANI LKKGHEIGNG
GITVSSSLLD KSTEEICKEI YEVDNLLRKI GVNTKAYMPG YGYVDVEVQE ALSVINKIHG
IKGYELFTYS KSPINHKYKN MNAEEVVKDY LNLNTYMSLR KGEIVYFRLD SDLFEDKNTV
ANIIELITAN YVKNGHANKY NEATQSYVLV EKPLNYSVET LSELQHTMES ASQLGRYRMA
DNINSLIRRS YEEALSMMKS NYIGNKYVDL SDLSEEEQVL MDKTGTIDTN GEDVIFFTFD
DWGGDPVVNE ILDVLNKHKV KGSFFVISKY IDTNGDVSNA NPNLLRTIAF NGHDIGSHNY
NHETLDTNKN KLEISLVKSY DAMANVIGDL NSLRTYFRPP TLLVKKEGLA QVFESGFKYS
INGNISTHDY ESSSSQEIVH SLEESLIKGR GNIIVMHMNN QSYYTAEALD IFLTNNENGV
YGTKYKIAKL SDYLE
//
