ID A0A084R2Z7_STAC4 Unreviewed; 805 AA.
AC A0A084R2Z7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=S40285_09432 {ECO:0000313|EMBL:KFA70582.1};
OS Stachybotrys chlorohalonata (strain IBT 40285).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Stachybotryaceae; Stachybotrys.
OX NCBI_TaxID=1283841 {ECO:0000313|EMBL:KFA70582.1, ECO:0000313|Proteomes:UP000028524};
RN [1] {ECO:0000313|EMBL:KFA70582.1, ECO:0000313|Proteomes:UP000028524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 40285 {ECO:0000313|EMBL:KFA70582.1,
RC ECO:0000313|Proteomes:UP000028524};
RX PubMed=25015739; DOI=10.1186/1471-2164-15-590;
RA Semeiks J., Borek D., Otwinowski Z., Grishin N.V.;
RT "Comparative genome sequencing reveals chemotype-specific gene clusters in
RT the toxigenic black mold Stachybotrys.";
RL BMC Genomics 15:590-590(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL659174; KFA70582.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084R2Z7; -.
DR HOGENOM; CLU_002458_2_1_1; -.
DR InParanoid; A0A084R2Z7; -.
DR OMA; PHMHARI; -.
DR OrthoDB; 54187at2759; -.
DR Proteomes; UP000028524; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018:SF26; DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G10920)-RELATED; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028524};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 544..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 620..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..170
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 193..378
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 398..614
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 698..789
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
SQ SEQUENCE 805 AA; 90475 MW; 4DA3AAA0DB4C2A2E CRC64;
MGGSFMTVDA KSQGSTSLAA VLSAFVPTWA TGMAFVAVFV LIRQRFPKSY YPRTYMGTIP
EKHRTPQDNL SSYFGWVKTM YSISDKFILY HSSLDAFLFL RFLRTIIFIC LVGSFLTWPT
LMPVNATGGG SSTQLDKVGI GNVVKINSYY AHAALAWIFF TFVMFTIARE RLWLICLRQA
WTLSKNSSSK LSSRTILFLS APEEALEENN MKRTFGEGAV RTWPAIDSTN LNRMVSDRDS
SVEQLEGAET RLIIRALKLI KKKQGNSQQS HEWSSYESLP QNIRDGIRPR HHAGCTMTGE
NVDSIRWYRQ RINEIVSEVE KARQERHESD GGGSAAVFVE FKTHADAQQA AQQVISPGIL
ELTPRYLGVA PKEVVWNNLF LSPERRISQE GVATALVLAL IVFWSLPSGL VDIFKIFGGA
TTTANELKVQ KWFYIFQVTQ VFLVTAVFSS GATVFSEILR RARNPSTIPR LLAKELPKSS
NYYLTYFLIQ GITASADNIL NCSDLLQYLV LGWAFDKTPR HMFNRYTNLK GIASGKVFPK
FANFAVIAIA YSCIAPLVLG FATTGLTLYY FSYRYNLLFV IQPKIDTRGL AYTLALQHLL
TGVYIAELAL IGLFGLASAT GPLILTVILF GLTVLYNLMT NKYLEPLEKH LPTDLATQLE
NDEAAPLLGS AEQGDSHIRH LGRQAHVPQR LLDPLERFFE PRFFATHQAI QRWLREDDEH
FEDEATTYNE EELAKAYTNP ALTSSTPIVW LPRDDAGVSR NEIAENKEAG IIATNGGAWV
DEKTRLRWND GDFEDVPLLK KCVSY
//
