ID A0A084VGP8_ANOSI Unreviewed; 234 AA.
AC A0A084VGP8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Vesicle-associated membrane protein 7 {ECO:0000256|ARBA:ARBA00039269};
DE AltName: Full=Synaptobrevin-like protein 1 {ECO:0000256|ARBA:ARBA00042194};
GN ORFNames=ZHAS_00004348 {ECO:0000313|EMBL:KFB37142.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EnsemblMetazoa:ASIC004348-PA, ECO:0000313|Proteomes:UP000030765};
RN [1] {ECO:0000313|EMBL:KFB37142.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC004348-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, phagosome membrane
CC {ECO:0000256|ARBA:ARBA00037875}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00037875}. Cytoplasmic vesicle, secretory vesicle
CC membrane {ECO:0000256|ARBA:ARBA00037803}; Single-pass type IV membrane
CC protein {ECO:0000256|ARBA:ARBA00037803}. Endosome membrane
CC {ECO:0000256|ARBA:ARBA00037867}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00037867}. Golgi apparatus, trans-Golgi network
CC membrane {ECO:0000256|ARBA:ARBA00037801}; Single-pass type IV membrane
CC protein {ECO:0000256|ARBA:ARBA00037801}. Late endosome membrane
CC {ECO:0000256|ARBA:ARBA00037845}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00037845}. Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00037863}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00037863}.
CC -!- SIMILARITY: Belongs to the synaptobrevin family.
CC {ECO:0000256|ARBA:ARBA00008025}.
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DR EMBL; ATLV01013047; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE524836; KFB37142.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084VGP8; -.
DR STRING; 74873.A0A084VGP8; -.
DR EnsemblMetazoa; ASIC004348-RA; ASIC004348-PA; ASIC004348.
DR VEuPathDB; VectorBase:ASIC004348; -.
DR VEuPathDB; VectorBase:ASIS017378; -.
DR OMA; NTKLMIM; -.
DR OrthoDB; 664519at2759; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd14824; Longin; 1.
DR CDD; cd15871; R-SNARE_VAMP7; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 3.30.450.50; Longin domain; 1.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR010908; Longin_dom.
DR InterPro; IPR001388; Synaptobrevin-like.
DR InterPro; IPR042855; V_SNARE_CC.
DR PANTHER; PTHR21136; SNARE PROTEINS; 1.
DR PANTHER; PTHR21136:SF179; VESICLE-ASSOCIATED MEMBRANE PROTEIN 7; 1.
DR Pfam; PF13774; Longin; 1.
DR Pfam; PF00957; Synaptobrevin; 1.
DR PRINTS; PR00219; SYNAPTOBREVN.
DR SMART; SM01270; Longin; 1.
DR SUPFAM; SSF58038; SNARE fusion complex; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS50859; LONGIN; 1.
DR PROSITE; PS50892; V_SNARE; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU00290};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 87..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..110
FT /note="Longin"
FT /evidence="ECO:0000259|PROSITE:PS50859"
FT DOMAIN 126..186
FT /note="V-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50892"
SQ SEQUENCE 234 AA; 26697 MW; 586540DC144408DF CRC64;
MPILYTVVTR GQIVLARYAE CVGNFAEVTE LIVPKIQLED HKLTYLHGNY LIHYICENRV
IYLCITDDRF DRAKAFMFLQ DVQQRFIATY GLAVATAIAY AMNSEFSRVL SARMRSYNEG
GQQLDAISRV NGEIDELRDI MVKNIENITN RGERLELLVN QTETLRNSSV TFRQTSRNLA
RTMFWRNVRI YFLVAALVLF AIYVIVSMAC KGLLWEGCIH SSAPQPTQPP SGGL
//
