ID A0A084VH68_ANOSI Unreviewed; 357 AA.
AC A0A084VH68;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Protein tweety homolog {ECO:0000256|RuleBase:RU361114};
GN ORFNames=ZHAS_00004690 {ECO:0000313|EMBL:KFB37312.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB37312.1};
RN [1] {ECO:0000313|EMBL:KFB37312.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC004690-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- FUNCTION: Probable chloride channel. {ECO:0000256|RuleBase:RU361114}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the tweety family.
CC {ECO:0000256|ARBA:ARBA00009849, ECO:0000256|RuleBase:RU361114}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361114}.
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DR EMBL; ATLV01013146; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE524842; KFB37312.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084VH68; -.
DR EnsemblMetazoa; ASIC004690-RA; ASIC004690-PA; ASIC004690.
DR VEuPathDB; VectorBase:ASIC004690; -.
DR VEuPathDB; VectorBase:ASIS011338; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR006990; Tweety.
DR PANTHER; PTHR12424:SF18; PROTEIN TWEETY-2; 1.
DR PANTHER; PTHR12424; TWEETY-RELATED; 1.
DR Pfam; PF04906; Tweety; 1.
PE 3: Inferred from homology;
KW Chloride {ECO:0000256|RuleBase:RU361114};
KW Chloride channel {ECO:0000256|RuleBase:RU361114};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|RuleBase:RU361114};
KW Ion transport {ECO:0000256|RuleBase:RU361114};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361114};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361114};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361114};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361114}.
FT TRANSMEM 166..187
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 303..322
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
SQ SEQUENCE 357 AA; 38863 MW; 94C64F7C74B9B0A7 CRC64;
MRARREDQLP PECAYPANRN ARVPRGVKIY GITCGPDSSW LADEVREVST FRKGESTFPP
ATKDAFVPKL KDVQYTYCST VGTNRYVLRL NESKVHVDRA KESLETVNSI GMDLYPGIQI
SSKVNKINGE LDDSKRQLTA LSVMLDRRTV AEHYADATRS LCEGGLLGLT LMLLASLVSA
AILSLLVCVD SHTWIYLTKK RPGYEDKAET TPLFPAGANA SPSAPIIASG TMTVNRTLLH
AQAATTNGST VGGPAVGGAG ATGTLIPTSG RNGTTHGMRG FASYSGDESP PPDYNVVVHD
NRHGFFVLIF ALSYLLLGSG SLGRRLRLEC LYGHRHLFRC FTLHFKQPPE TGRRSIF
//
