ID A0A084VL11_ANOSI Unreviewed; 1835 AA.
AC A0A084VL11;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=AGAP008906-PA-like protein {ECO:0000313|EMBL:KFB38655.1};
GN ORFNames=ZHAS_00006048 {ECO:0000313|EMBL:KFB38655.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB38655.1};
RN [1] {ECO:0000313|EMBL:KFB38655.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC006048-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ATLV01014395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE524970; KFB38655.1; -; Genomic_DNA.
DR STRING; 74873.A0A084VL11; -.
DR EnsemblMetazoa; ASIC006048-RA; ASIC006048-PA; ASIC006048.
DR VEuPathDB; VectorBase:ASIC006048; -.
DR VEuPathDB; VectorBase:ASIS000964; -.
DR OMA; MENQVYE; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032629; DCB_dom.
DR InterPro; IPR015403; Mon2/Sec7/BIG1-like_HDS.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR046455; Sec7/BIG1-like_C.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF375; LD29171P; 1.
DR Pfam; PF20252; BIG2_C; 1.
DR Pfam; PF16213; DCB; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF09324; Sec7-like_HDS; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 678..867
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 608..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1508..1559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1609..1630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..668
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1835 AA; 203190 MW; E1C4B7699D10D447 CRC64;
MQTTVASSNA GSTGNNTSGG SSSNTNNTAY QTTGGSSGKG ISGISALTTK TKEMFILRAL
EKILSDKDIK RSHHLQLKRA CDVALEDIKE ELKQAGHADS NGETPVPSAA LPLPKNDSGN
IINAEKYFLP FELACQSRTP RIVVTALDCL QKLIAYGHLT GNIPDSSNPG KFLIDRIVTT
ICNCFMGPQT DEGVQLQIIK ALLTVVTSQH VEVHEGTVLQ GVRTCYDIYL SSKNLINQTT
ARATLTQMLN VIFTRMENQA FEALAASQNQ PLPAAALPQT SLASPTVVDE TKPPLPAGEK
HPDYDAMRAI VEEIVDGVIA QAASSVAEET GAVSPTTPVA NNEASETVSI GGISNGGTDS
TSIARVPSQE SMEVTSENDS IVTAKFTHIL QKDAFLVFRA LCKLSMKPLP EGHPDPKSHE
LRSKILSLHL LLSILQNAGP VFRSNEMFIM AIKQYLCVAL SKNGGSAVPE VFELSLSIFV
ALLSNFKIHL KKQIEVFFKE IFLNILEAPS SSFEHKWMVI QALTRICADA QSVVDIYVNY
DCDFSAANLF ERLVNDLSKI GQGRQALELG TSVNQEKSMR IRGLECLVSI LKCMVEWSKD
LYVNPNSQTT LGDPPGGGGG VGGKSGGLNV SGTSIVEETT QELVMKSHGG SSVSINSLGS
TNTSGGGGNR EVLDLPEELE ERKQRKEVME TGIEMFNRKP KKGIAFLQER GLLGTTVEDV
ARWLHEDERL DKTQIGDYLG ENDEQSRAVM CGYIDAMNFA ELDIVAALRY FLEGFRLPGE
AQKIDRLMEK FASRYCDCNP NNTLFASADT VYVLAFSVIM LTTDLHSPQV KHKMTKEQYI
KMNRGISDNK DLPEEYLSQI YDEIAGHEIK MKNTVANKPA GKQIIVNEKK RKLLWNLEME
ALSTTAKNLM ESVSHVKASF TSAKHLEHVR PMFKMAWTSF LAAFSVGLQD CDDPEIASLC
LDGIRCAVRI ACIFHMSLER DAYVQALARF TLLTANSPIN EMKAKNIDTI KTLIMVAHTD
GNYLGSSWLD IVKCISHLEL AQLIGTGVRP EFLSGPASHR DTLDPSAKEH IGETSSQSIV
VAVDRIFTGS IRLDGDAIVD FVKALCQVSL DELTRPQPRM FSLQKIVEIS YYNMGRIRLQ
WSRIWQILGE HFNAVGCNTN EEIAFFALDS LRQLSMKFIE KGEFTNFRFQ KDFLRPFEHI
MKKNNSPAIR DMVVRCVAQM VNSQAHNIKS GWKNIFSVFH LAAGDHDEAI VELAFLTTGK
IITELYRSQF PIMIDSFQDA VKCLSEFACN ARFPDTSMEA IRLVRTCALC VNESPQLFAE
HAGMENDVSV PEEDRVWVRG WFPMLFSLSC VVNRCKLDVR TRGLTVLFEI VKTHGDAYRA
NWWRDLFNVL FRIFDNMKLP EHQTEKAEWM TTTCNHALYA IIDVFTQYFD MLGPMLLADL
YCQLHWCVQQ NNEQLARSGT NCLENLVISN GLKFGEDTWD KTCQCMLDIF NSTLPRELLT
WKPDPLPQSI AAPGAGQPPS AVVRGNHENG DLPRHGILKR SGSQHSVHTQ DHPHHGDSSA
ANTSVLFSNL LIKCVVQLEL IQTIDNIVFF PATSRKEDAE TLAQATAELS SVTSHPAGGH
PSYPSSLSGE ECQREEQGMY SYLNTPHLLQ LVDCLLQSHR FAKQFNSNND QRTVLWKAGY
KGSLKPNLLK QETQSLACVL RILFKMYSDE SRRRDWQDIE SRLIGVLHRG TGLLPVATGR
TAPGRLDIAA AAGDDAITQD VRCEILHLFL LLFPPLKFAA HIASYYVFLC DLTCVDLKPE
LRTVLRRVFL RISPVFGISN ANGNGAGTTV PLAAT
//
