ID A0A084VQ17_ANOSI Unreviewed; 1156 AA.
AC A0A084VQ17;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Echinoid {ECO:0000313|EMBL:KFB40061.1, ECO:0000313|EnsemblMetazoa:ASIC007522-PA};
GN ORFNames=ZHAS_00007522 {ECO:0000313|EMBL:KFB40061.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB40061.1};
RN [1] {ECO:0000313|EMBL:KFB40061.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC007522-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; ATLV01015104; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525002; KFB40061.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084VQ17; -.
DR STRING; 74873.A0A084VQ17; -.
DR EnsemblMetazoa; ASIC007522-RA; ASIC007522-PA; ASIC007522.
DR VEuPathDB; VectorBase:ASIC007522; -.
DR VEuPathDB; VectorBase:ASIS001034; -.
DR VEuPathDB; VectorBase:ASIS004415; -.
DR OMA; NGKYECR; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00063; FN3; 1.
DR CDD; cd00096; Ig; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF164; MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 1; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF13895; Ig_2; 2.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 774..795
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..118
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 125..193
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 219..308
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 313..421
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 426..523
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 530..638
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 994..1047
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1060..1095
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1109..1145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1022..1046
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1156 AA; 127755 MW; C279F18998F4C51B CRC64;
MLATVGVQKT NDRSRVEHRT FFFLPTHARR ISTREQNNYP RVKVGPENPL RVERDSTAML
ECAVDSKPKV PNVRWTRNGR LISSSPSHPI QRVSVQDAGN YACSADNGLG KVGEQIITLD
VLFAPIVVIE SKTWEAEERS TVTIRCNVTS NPPPVTIEWF KEGSPDFRYA GDILQLRDIK
AEHAGRYVCR AVNMMKPYNG KIVERVGNST VALLVRHRPG QAYINPSKPV VHVGNGVTLT
CSANPPGWPV PQFRWFKDAM GELSNTKTIL AQGPQYVIPR AHLGSEGSYH CHAVNELGNG
PMATINLEVH QPPQFIGKMQ QHMTKRIGDT DFSATCQAQG KPRPMVRWLK DGRDITTDAN
MYRISTNNND ALRGIVTVQS TLLFQGKARP HKNQLLPSDR GTYTCLFENE VSTANASMNL
RIEHGPIVLH QYNKVAYEIN ENAAVVCRVQ AYPKPEFQWQ LGTNTAALSM SSDGHYEINT
TTDNNDIYTS VLRINRVKHE DYGDYTCRVG NSIETIRAPI RLQPKGPPEK PTNLGVADVG
SNYVSLVWDP GFDGGITNTK FFVSFRKVAI PHHDQVKEDC GIVQQVSSEW MEYDCQRDVP
CSVTPLDQYQ SYVFKVKALN SKGHSEPSNE VATTTKISKI PVPLHVGFDP DTKQLGLSVG
ATCLALIAVV ETIGFHESPI ATWQIVQSIP LAVSGSGTTY KEQVLENMYS ARRSSGRSMA
SDDDFPMALE EEIPPKVRVK LCLKSSHEYC GEYMDAEIGP ALIHDSPFIA TPTLIAIVVS
CVVFALFVGL MLMFCRCKRN QTKKSTQSKD YEMDSVRPSI VAQQSQAPPP YYPTTPGLDN
KALEHSMDLA LALEDQKTSV YATHNGYGYH TGTSIQVASH SLPANEWVTM GYTENSYTNS
NNGGSVNSQD SIWQLKGGAP PPGTTTLAIG LQPLSMAGLH GGGSAYATTT TTTTAAAAGS
STPGLAYGYD PIASHSSIYG GGGAVTLADE YNQYPHPAAT PSQHGGEDDY LHHHHHHQQQ
QQQQQLHHVA ALRQSQNPSR QQEYCGDSYA SVHKAKKRLD QPSHFDSSYH DVSGLPDPYL
DQHQQHQLDQ QEDSKSSLLQ LNHPQDHGSL HLHAQQQQQP SSSQQQQPQP IYEDNLESGY
STPNSRNRRV IREIIV
//
