ID A0A084VYA6_ANOSI Unreviewed; 597 AA.
AC A0A084VYA6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=AGAP009050-PA-like protein {ECO:0000313|EMBL:KFB42950.1};
GN ORFNames=ZHAS_00010823 {ECO:0000313|EMBL:KFB42950.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB42950.1};
RN [1] {ECO:0000313|EMBL:KFB42950.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC010823-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ATLV01018352; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525231; KFB42950.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084VYA6; -.
DR STRING; 74873.A0A084VYA6; -.
DR EnsemblMetazoa; ASIC010823-RA; ASIC010823-PA; ASIC010823.
DR VEuPathDB; VectorBase:ASIC010823; -.
DR VEuPathDB; VectorBase:ASIS004405; -.
DR OMA; ECEPQTR; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:UniProt.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.5.300; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR032406; CLZ_dom.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF16526; CLZ; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 91..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 410..516
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT COILED 552..597
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 597 AA; 67384 MW; D7A1A8D8F68F1288 CRC64;
MGRIPSIPEP SSGRRSKLSS LRRSLNALRC RISKRGRSKP PDQFLDKFSA ASATSDTRLH
QAGCVAPQAV PSDGVCSRLS VDPSLPSHYR WLSLVSLAVL YNIVFVIGRA VFWELNKQAA
VLWWILDYLC DFIYLADTLV HCHEGYLEQG LLVRDASKLR KHYFSKQRWW LDVVSMLPTD
LAYIWWAPSS CAATRLPCPI IVRINRLLRL PRMWEWFDRT ETATGYPNAF RICKVVLAIL
VLIHWNACLY FAISYALGFS TDNWVYNING PKNLTLSRQY IYSFYWSTLT LTTIGETPTP
ENDAEYLFVV ADFLAGVLIF ATIVGNIGSM ISNMNVTRVE FQNRMDGVKQ YMAFRKVGGE
LEARVIRWFA YTWAQSGALD EERVLAALPD KLKAEIAIRV HMDTLRQVRI FQDCEPGLLE
ALVLKLKLQV FSPGDYICRK GDVGKEMYIV KRGSLSVVAD DGITVLATLG AGSVFGEVSV
LEIAGNRTGN RRTANVRSIG YSDLFCLAKR DLWETLADYP EARASLTERG CQLLRKDGLL
DEAVFANAQQ TQDSLESGVA RLEQTVENLN LRLARLLAEY SASQAKLKQR ISKLEDR
//
