ID A0A084W7D9_ANOSI Unreviewed; 583 AA.
AC A0A084W7D9;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Gamma-glutamyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ZHAS_00014179 {ECO:0000313|EMBL:KFB46133.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB46133.1};
RN [1] {ECO:0000313|EMBL:KFB46133.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC014179-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ATLV01021228; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525315; KFB46133.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084W7D9; -.
DR STRING; 74873.A0A084W7D9; -.
DR EnsemblMetazoa; ASIC014179-RA; ASIC014179-PA; ASIC014179.
DR VEuPathDB; VectorBase:ASIC014179; -.
DR VEuPathDB; VectorBase:ASIS004842; -.
DR OMA; FMVIGSP; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0036374; F:glutathione hydrolase activity; IEA:InterPro.
DR GO; GO:0006751; P:glutathione catabolic process; IEA:InterPro.
DR Gene3D; 1.10.246.130; -; 1.
DR Gene3D; 3.60.20.40; -; 1.
DR InterPro; IPR043138; GGT_lsub_C.
DR InterPro; IPR000101; GGT_peptidase.
DR InterPro; IPR043137; GGT_ssub.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR PANTHER; PTHR11686; GAMMA GLUTAMYL TRANSPEPTIDASE; 1.
DR PANTHER; PTHR11686:SF75; GAMMA-GLUTAMYL TRANSPEPTIDASE, ISOFORM A; 1.
DR Pfam; PF01019; G_glu_transpept; 1.
DR PRINTS; PR01210; GGTRANSPTASE.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT ACT_SITE 390
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR600101-1"
SQ SEQUENCE 583 AA; 63257 MW; F35A75EF01022075 CRC64;
MVIILLNINK KKLLLLSVLA AIVIVALTLG LVLGLRSRDD DPKPSHARLT GGAVTSNGLE
CAAIGASILR QNGSAADAAI ATLFCEGVTC PQSMGLGGGF LATIYIREKG TAEALDAREV
APAAATQGMF INRTVSGGLA VAVPGEVKGY WELHQRYGRL DWKTLIEPTI KLCREGHVVT
GYLERILAPR ADLIRNEPSL AEVFINPETQ LPWKEGDRLK RLALADTLEV IAEEGVHALY
SRNGTLLPKL MRDLKQFGSI ITEDDFLNYE PRWLDAVHTS ISKSSQVYSI PLPGSGPILN
YMLNILDNFG DMRQGDPLSW HRLVESFKHG YGRRTRLGDP PFVRGIEDEL HKLASKTYAR
YIYETMSDNS TRSDFEHYGA EFANVPDQGT AHVSILAPNG DAIAVTSTVN SILGAKIRST
STGIVLNDEM DDFATPGLIN GYGLPASPAN YIVPGKRPMS SMTPTIVTDD TGDVRIVVGS
AGGSRITTAT MQLIVRHLMF GESLEAIIKT PRLHHQLAPM VVEYEKDFDP AVIAGLRERG
HVCNQAASDG GFAALTAIVR YADNRIEATY DPRRVGSTAI LTD
//
