ID A0A084W9P1_ANOSI Unreviewed; 1143 AA.
AC A0A084W9P1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 13-SEP-2023, entry version 35.
DE SubName: Full=AGAP004805-PA-like protein {ECO:0000313|EMBL:KFB46935.1};
GN ORFNames=ZHAS_00014947 {ECO:0000313|EMBL:KFB46935.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB46935.1};
RN [1] {ECO:0000313|EMBL:KFB46935.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC014947-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the formin homology family.
CC {ECO:0000256|ARBA:ARBA00023449}.
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DR EMBL; ATLV01021848; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ATLV01021849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525324; KFB46935.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084W9P1; -.
DR STRING; 74873.A0A084W9P1; -.
DR EnsemblMetazoa; ASIC014947-RA; ASIC014947-PA; ASIC014947.
DR VEuPathDB; VectorBase:ASIC014947; -.
DR VEuPathDB; VectorBase:ASIS005472; -.
DR VEuPathDB; VectorBase:ASIS016086; -.
DR OMA; MMPGFSP; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR043592; FMNL_animal.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR45857:SF4; FORMIN-LIKE PROTEIN; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 2.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765}.
FT DOMAIN 83..536
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 655..1055
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 1096..1129
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 216..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 447..544
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 941..998
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1032..1090
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 562..579
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..610
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..640
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1143 AA; 129230 MW; 10630A37AD4883BA CRC64;
MGLASSKAVN SIAVSSHGGA EMGNGRLSKD SVIVETSSSY PSADIQQQPC SILPSPSGSS
GIDTWKSSSC HVRQASIRSR NLQPMPDAGE LDRRFAKVLA SMDLPPDKAK LLKNYDNEKK
WDIICDQEMV QAKDPPAHYL TKLRTYLDPK ASRSHRKRKM VGESTSTQVL RDLEISLRTN
HIEWVKEFLD DENQGLDALI DYLSFRLAMM RHEQRIQEAK SESDEGLNPK ETSGINSSYG
SNEANHRLVS NGFMRPGLGD MMDSPSIKRR SRHIAKLNMG LTTDDIHVCI MCMRAIMNNK
YGFNMVIQHR EAINCIALSL IHKSLRTKAL VLELLAAICL VKGGHEIILF AFDNFKKVCS
EQRRFQTLME YFMNYELFNI DFMVACMQFV NIVVHSVEDM NYRVHLQYEF TALGLDEYLE
KLRLTESEEL QVQISAYLDN VFDVAALMED SETKTAALER VNELEDELGR ALDQASEIER
EALFKIGELE AELSRTRCER DELYNKQLAV EDEVAKLKRA LKQHEQESQN RKSMLLELEN
LTKTLPKGTS IADVSNLLAK GGLSELSPTN GGNGGGQQQQ APPIPPPPAP PIPSAGAPMP
PPPPCPPGSG LPNGGANEPP KAPPKPPTFI PVPPPMGGPP GFHNALHCTD GAMTIKRKVQ
PKYKLPTLNW VALKPNQVRG TIFNELDDEK LHRQIDFVDF EERFKIGMGG PLTNGNCDMD
GLTAFPSKRF KKPEHISLLE HTRLRNIAIS RRKLEMPIET VIKAINNLDL KLLSLENVEL
LQKMTPTDQE QKMYKEYVIE KKDLNQLTEE DKFMLQLTKV ERISSKLSIM NYIGNFFDSL
HLISPQVYSI ISASSSIKSS KKFRAVLEVI LAFGNYLNSS KRGPAYGFKL QSLDTLLDTK
SNDKRMSLMH YIVATIRLKF PELMNFDTEL FCIDKAAQVS LEMLISDMSE LEKGMEAVRK
EVDLRGKGTQ SHVLRDFLAN SEEKLKKIKS ECKTAQESFK ECIEYFGESS RNADANAFFS
LLVRFVRAFK TCDQENEQRR RLEAAALQAS TKKDEEEQVV MRNNKINSQK KQQEAVINEL
KLKAHAVREK KLLQQDEVYN GALEDILMGL KNEPYRRADA VRRSQRRRID SNRLSRTMEE
VDF
//
