ID   A0A084WD92_ANOSI        Unreviewed;       818 AA.
AC   A0A084WD92;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=AGAP008007-PA-like protein {ECO:0000313|EMBL:KFB48186.1};
GN   ORFNames=ZHAS_00016255 {ECO:0000313|EMBL:KFB48186.1};
OS   Anopheles sinensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=74873 {ECO:0000313|EnsemblMetazoa:ASIC016255-PA, ECO:0000313|Proteomes:UP000030765};
RN   [1] {ECO:0000313|EMBL:KFB48186.1, ECO:0000313|Proteomes:UP000030765}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA   Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA   Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA   Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT   "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT   of mosquito competence for malaria parasites.";
RL   BMC Genomics 15:42-42(2014).
RN   [2] {ECO:0000313|EnsemblMetazoa:ASIC016255-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; ATLV01022956; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KE525338; KFB48186.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A084WD92; -.
DR   STRING; 74873.A0A084WD92; -.
DR   EnsemblMetazoa; ASIC016255-RA; ASIC016255-PA; ASIC016255.
DR   VEuPathDB; VectorBase:ASIC016255; -.
DR   VEuPathDB; VectorBase:ASIS020843; -.
DR   OMA; IREWDRY; -.
DR   Proteomes; UP000030765; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR015157; TMA7.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF169; CULLIN-1; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   Pfam; PF09072; TMA7; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030765}.
FT   DOMAIN          418..651
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          755..818
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        757..796
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   818 AA;  94341 MW;  085608A56C4704FA CRC64;
     MSKLNSHGAT GLKNINLEEI WTDLEGGIKQ VYKREHSLGI ARYMELYTHV YNYCTSVHQQ
     PNCRTGSSKV SKKGMNAPPG GAQLVGQELY KRLKEFLENY LVRLHQNGID LMDEEVLSFY
     TKRWEEYQFS SKVLNGVCAY LNRHWVKREC EEGRKDVYEI YQLALVTWRG NLFKHLNKQV
     TNAVLKLIER ERNGETINSR LVSGVINCYV ELGLNEEDPH AKGQNLSVYK ESFENIFLED
     TERFYTRESA EFLRENPVTE YMKRVELRLN EEQKRVQVYL HESTLERLAE KCERVLIQNH
     LDQFRTEFQN LLNSDKNQDL ARMYSLVARI KSGLSELKEI LETHIHNQGL AAIEKCGDSA
     VNDPKIYVQT ILEVHKKYNA LVLIAFNNDS GFVAALDKAC GKFINTNAVT EVSRSASKSP
     ELLAKYCDLL LKKSSKNPEE AELEDTLNQV MVVFKYIEDK DVFQKFYSKM LAKRLCHHMS
     ASDDAEASMI SKLKQACGFE YTSKLQRMFQ DIGVSKDLND QYRKHHEKLR DLRSSGQNEI
     DFSILVLSCG SWPFGQGFTF SLPFELEQSV QRFNSFYAKQ HSGRKLNWLY NMCRGELITN
     CFRMRYTLQA STFQMAVLLQ FNEETAWSIK QLGENTGINN ENLIQVLQIL LKTKLLTCYE
     DEGKLQPEST IELNKDFKNR KLRININFPL KTELKVEQEA THKNIEEDRK ILIQAAIVRI
     MKMRKILNHT QLVGEVLNQL STRFKPKIQV IKVGMSGREG GKKKPLKAPK KEQGEMDDDD
     VAFKQKQKEA QKALEAAKQK AAKGGPLLQG GIKKSGKK
//