ID A0A084WDS6_ANOSI Unreviewed; 477 AA.
AC A0A084WDS6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=AGAP005012-PA-like protein {ECO:0000313|EMBL:KFB48370.1};
GN ORFNames=ZHAS_00016491 {ECO:0000313|EMBL:KFB48370.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB48370.1};
RN [1] {ECO:0000313|EMBL:KFB48370.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC016491-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GHMP kinase family. GalK subfamily.
CC {ECO:0000256|ARBA:ARBA00006566}.
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DR EMBL; ATLV01023057; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525340; KFB48370.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084WDS6; -.
DR STRING; 74873.A0A084WDS6; -.
DR EnsemblMetazoa; ASIC016491-RA; ASIC016491-PA; ASIC016491.
DR VEuPathDB; VectorBase:ASIC016491; -.
DR OMA; GFHDTYF; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004335; F:galactokinase activity; IEA:InterPro.
DR GO; GO:0006012; P:galactose metabolic process; IEA:InterPro.
DR Gene3D; 1.20.1440.340; -; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.3170; -; 1.
DR InterPro; IPR000705; Galactokinase.
DR InterPro; IPR019741; Galactokinase_CS.
DR InterPro; IPR019539; GalKase_N.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR006203; GHMP_knse_ATP-bd_CS.
DR InterPro; IPR006206; Mevalonate/galactokinase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00131; gal_kin; 1.
DR PANTHER; PTHR10457; MEVALONATE KINASE/GALACTOKINASE; 1.
DR PANTHER; PTHR10457:SF7; N-ACETYLGALACTOSAMINE KINASE; 1.
DR Pfam; PF10509; GalKase_gal_bdg; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR PIRSF; PIRSF000530; Galactokinase; 1.
DR PRINTS; PR00473; GALCTOKINASE.
DR PRINTS; PR00959; MEVGALKINASE.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00106; GALACTOKINASE; 1.
DR PROSITE; PS00627; GHMP_KINASES_ATP; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 28..76
FT /note="Galactokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10509"
FT DOMAIN 140..204
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 367..437
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 477 AA; 52450 MW; 328334AE599BA506 CRC64;
MTTDTSDLCV QVLGTIPSCE RISRLVKCFS NEFSRAPSFV VRCSGRVNII GEHVDYCGYP
VFPMAIEQTI LLAVAPSNDN LLHIKNANNN FKPYKCNVLT FSIDVPSVGG PNWYQYVLCG
VKGILDSTAI KHDAPRGMLI MLSGNIPPAS GLSSSSAIVS ATVLGTAYMH NATLNKQTLA
TISAECEKFI GTQGGGMDQA IAYLAQEGCA QLIEWNPLRA TPIQLPSNAV FVIANSLSEA
NKAATSDFNQ RVVECRLASR LLAKQMKLNW RDLNRFADLQ KALGYSLEEM ESLVNGKLPQ
NSYTRAELLN LLEVTEDDFV ENLLTPNTRN SQTFKLKQRA LHVFQEALRV QQFIETAKTT
SDDSVSRMKT LMRQSHESLR SLYECSHENL DRIVQISDQL GVGTRLTGAG WGGCVVALCD
GLDESKRFVE ALKNEFYASI PKAQSCDIAT LCFATSPQRG AEIYLMDKQN DILSLSS
//
