ID A0A084WK39_ANOSI Unreviewed; 446 AA.
AC A0A084WK39;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=AGAP006216-PA-like protein {ECO:0000313|EMBL:KFB50583.1};
GN ORFNames=ZHAS_00018899 {ECO:0000313|EMBL:KFB50583.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB50583.1};
RN [1] {ECO:0000313|EMBL:KFB50583.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC018899-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 2 family. Mth
CC subfamily. {ECO:0000256|ARBA:ARBA00008979}.
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DR EMBL; ATLV01024093; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525349; KFB50583.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084WK39; -.
DR STRING; 74873.A0A084WK39; -.
DR EnsemblMetazoa; ASIC018899-RA; ASIC018899-PA; ASIC018899.
DR VEuPathDB; VectorBase:ASIC018899; -.
DR VEuPathDB; VectorBase:ASIS008803; -.
DR OMA; AYCEMED; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15039; 7tmB3_Methuselah-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR036272; Methuselah_N_sf.
DR PANTHER; PTHR47154; G-PROTEIN COUPLED RECEPTOR MTH-RELATED; 1.
DR PANTHER; PTHR47154:SF2; G-PROTEIN COUPLED RECEPTOR MTH-RELATED; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR SUPFAM; SSF63877; Methuselah ectodomain; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023040};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 213..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 210..446
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 446 AA; 50528 MW; DBCB99D73B7AE96B CRC64;
MTKSSSYQRV TIRQGSGWCL WQRIFLCVMV ALCCGTGELS FGISDVRGAL LCLPEESVNI
TDGTVQEDGS IVHDDIRYGP EQYFNINSDV FGCVCLVRQC ILIYCEDQTT YPSGTECPLE
ELQVNVSTAA STHTLVDILN NPRYHLIFRT PHCSPDRILG LPPQDYVLQS DGRLAYGPSL
FNYRQFALML ENKTGETLAA YCEMEDVQAH HQWYSIGILV SLPFMVATFV VYALLPELQN
IPGKSLMCYV ASLTVGYLLL ALMRFSLYEH QSGWCIGTAY IVYFALLASF FWLNVQAFDI
YWTFGGSRGR TSERRKFLYY SLYAWGVPLT LLAFVLLVDH TDFMDDKLRP LFGHERCLFR
GRLSRANGKE CNPPEGVLIV CSDIPVAGDK LIGFVYMYLP LALLVGANVF FFGMSAFRIY
RMQQSAATAL SGDSRRHTKY EKDRYR
//
