ID A0A084WNG0_ANOSI Unreviewed; 2006 AA.
AC A0A084WNG0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=AGAP007533-PA-like protein {ECO:0000313|EMBL:KFB51754.1};
GN ORFNames=ZHAS_00019848 {ECO:0000313|EMBL:KFB51754.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB51754.1};
RN [1] {ECO:0000313|EMBL:KFB51754.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC019848-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ATLV01024599; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525352; KFB51754.1; -; Genomic_DNA.
DR STRING; 74873.A0A084WNG0; -.
DR EnsemblMetazoa; ASIC019848-RA; ASIC019848-PA; ASIC019848.
DR VEuPathDB; VectorBase:ASIC019848; -.
DR VEuPathDB; VectorBase:ASIS014339; -.
DR OMA; HNMCQQF; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR CDD; cd18026; DEXHc_POLQ-like; 1.
DR CDD; cd08638; DNA_pol_A_theta; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.20; -; 1.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR046931; HTH_61.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048960; POLQ-like_helical.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF62; DNA POLYMERASE THETA; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF20470; HTH_61; 1.
DR Pfam; PF21099; POLQ_helical; 1.
DR PRINTS; PR00868; DNAPOLI.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765}.
FT DOMAIN 445..618
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 670..875
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 915..934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1279..1301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..183
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2006 AA; 224548 MW; 49C8D4C1EB766C3A CRC64;
MTEFSQSLQL GDNTLEALER QLSKPFTPPS VTAADRRTTR SSQNQRTNRQ SSTEEVIEES
PTNVKGSAEL SRQRSVRERL QIISTQSRTR KTSKRTTKRS NTTLDGSQCK DQQVVGATSK
DGQSSSQVGE KENIPDGFER ALPLESSARG SKARTDKPLV GSCSRAIESN RASRDDDPSP
EKIARISNNE YDDLFQSSIF SVDAARSQTL QSHQDDPKET SYHTLFDQSD FTLDKYDRTT
PVQLRPEPSE TEQYPLRSSL ASMSMSESEQ EIFSETVFDR AISSDLMIEE AEENTGLEES
LRVTDSANDT IEDVLLNIEN VTFSQPLGPI GSGMFRQHPN GDQSNDVLDL IESDKTGSGP
TLQAMLTTIR NTNDSVVLSE NCNRTQSTSL VKETREQLDC SMSFDNSKDL RSLASWGLPT
TVSDEYAKKG IVELFQWQVD CLSRKEVLLE GKNLVYSAPT SAGKTLVSEF LMAKTIAERK
LKVLLILPFV AVAREKMLYL RDLLASSGMR VEGFYGGYHP PGGFESVDLA VCTIEKANSI
VNRLLEQSNL SSLGMVVVDE AHLISDPSRG YILELLLTKI RFVAKQNEHR IQVVCMSATL
PNIDLLARWL DAELFHTDFR PIELVEMIKI GNTIYGAAPI EGTRRALRVL DGTLLDCPIP
KDPDHVALLC LETILEGCSV IVFCPSKDWC EQLAIALAST LHGLRKESHP HRELSERING
QFDGDRLEEV LLQLRNCPAA LDSVLEKTVR YGVAFHHAGL TTDERDIIEA SFRDGALRII
VATSTLSSGV NLPARRVIVR TPKFGGRQMS ALTYKQMIGR AGRKGRDTLG ESVLICSPTE
EKIGRELVGT VLPPVRSCLD SENYTHLKRA VLEIIASGSA STTKELESFV NTTLYSCERG
YRFEVDDQLI LSAKRVQKQP PQPPSNENDE ESESDPIASC IEFLLEYEFI RLQKGGAGAT
EEKEDAKMVH LSATRLGHAC LAASLPPKDG FLLFSELQKA RQCFVLESEL HAVYLVTPYS
VAYQWQQIDW MDFLDLWEKL PVASKRVGEL VGVKESFMVR AMRGTGNLDY RALQIHKRFY
TALALLELVN EVPLCTVARK FKCCRGLLQS LQQISATFAG IVTSFCHALH WTLVQLIVSQ
FRERLFFGVA HELLDLMRIP SLNGQRARLL YDGGIPGLAE LANADRLTVE KILYNRTSFE
AERLREDENE YDAARRKNLR NLYLTGRAGM TVEEAARLLI QEARTFLQLE HGLENPNWTT
QDEAVKTSTT PELAETATVM STNPVEQQPK RQDQSSSSVL SRVDSSVGCS GQFHNSLLMT
DHRRSADNDD RYPKSLRIVD VCADRLVYEQ FLKTVNEYDR LSVACGVARD ESVPPDGAED
LKIGGHLLKK VPQAAVEFYG RHSKRSFTFD GDLYLAGVGI TGCKGGQPKD ATVYYMDLQN
GTVIDDEEKR QTIRTLLQKE GLSVTLLDAK DQLKVFYKAG LLRSVGVLEE VFATVQDPRV
ACWLMQTEEK TLTVEAMIAR HCPGLQQAEL RWTGQRWISP KWIGYGMNHH SPIDAKQRCA
VECLIVDHLM DSVLDRLAEN GGETLLTCFA SREMPVQLAL ARCELDGFPV DRHQLSALIG
RLKACRERIA EDARKLNGNR RLDFGSSRAV AIALRLAAAG ENRKRIRTTR QTLERLDSPL
AALVIAYRKI ESNLTRTIEP LYRAICPRTG RIHGRSFCYT STGRITMHEP NLQTVVKDFD
VPGSPIAERF SCRSTFICSH PGVVLLSADF CQLELCILTH LSQDRRLMEA LSNQAVGKRD
VFRSLAARWN QLEREADVSD ELRNRTKAIV YGVIYGMGVR SMAAELQIDE DAARTLMEQF
HASYPDIRRY TERVVQLTRQ LGYIETLTGR RRYLPAINSA DSSERAEAER QAVCTTIQGS
AADILKNAIV RMVRNLRKYR DVLDLSTIRL VLHLHDELIY EVPRGQLPKV AKILRSSMEN
CAKLSVPLRV KLKAGSSWGK LEELSL
//
